Evidence brief
Platelet-Rich Plasma in Orthopaedic Surgery: Evidence Review
Heterogeneity in PRP preparations limits conclusions
Some evidence for knee OA symptom relief
Limited evidence for tendinopathy
ACL graft maturation may be enhanced
Rotator cuff healing benefit uncertain
PRP evidence remains mixed with significant heterogeneity in preparations and applications. Some promising results for specific indications but not universally recommended.
Be evidence-based when discussing PRP. Acknowledge: varying preparation methods, inconsistent results across studies. Best evidence for: knee OA (short-term), chronic tendinopathy (some benefit). Avoid overpromising to patients. Discuss cost-benefit.
Level I
Systematic review of RCTs or high-quality RCT