Anterolateral (Anterior, Brachialis-Splitting) Approach to the Humerus

TraumaIntermediate

Anterolateral (Anterior, Brachialis-Splitting) Approach to the Humerus

Comprehensive guide to the anterolateral (anterior) approach to the humerus and its brachialis-splitting distal extension, including the deltopectoral-derived proximal interval, the brachialis-splitting internervous plane (musculocutaneous medially, radial laterally), MIPO windows, and radial nerve protection for plating of proximal-to-distal-third diaphyseal fractures.

High-yield overview

Anterior / Brachialis-Splitting | Proximal-to-Distal-Third Shaft | Workhorse for Anterior Plating & MIPO

Surgical Imaging

Anterior arm musculature: biceps brachii lies superficially (left panel); with biceps cut away (right panel) the brachialis is exposed lying deep to it, alongside brachioradialis in the forearm. The a
Anterior arm musculature: biceps brachii lies superficially (left panel); with biceps cut away (right panel) the brachialis is exposed lying deep to it, alongside brachioradialis in the forearm. The aCredit: OpenStax College via Wikimedia Commons (CC BY 4.0)
Schematic of the brachialis muscle (red) arising from the broad anterior surface of the distal humeral shaft and inserting on the ulna. This is the muscle split longitudinally in the approach; its lat
Schematic of the brachialis muscle (red) arising from the broad anterior surface of the distal humeral shaft and inserting on the ulna. This is the muscle split longitudinally in the approach; its latCredit: Frederick Henry Gerrish (1845-1920) via Wikimedia Commons (Public domain)

Indications & Rationale

Primary indications

Open reduction and internal fixation of proximal-third and middle-third humeral shaft fractures; anterior MIPO (minimally invasive plate osteosynthesis); fixation of many distal-third shaft fractures via the brachialis-splitting extension; biopsy/excision of anterior diaphyseal lesions; non-union/malunion surgery requiring anterior plate access.

Why anterior rather than posterior

Keeps the radial nerve out of the operative field for proximal-to-middle-third fractures (the nerve is posterior in the spiral groove); patient lies supine (no lateral/prone positioning); is the established corridor for anterior MIPO; and allows extension proximally to the shoulder and distally to the elbow on one supine set-up.

When to prefer the posterior approach instead

When the radial nerve must be directly explored, decompressed, or repaired (e.g. open fracture with palsy, secondary palsy after manipulation), or for distal-third fractures needing maximal exposure and direct nerve visualisation, the posterior (triceps-splitting/-sparing) approach is generally preferred.

Relative cautions

Distal-third comminution where bicortical distal screws endanger the radial nerve; very proximal fractures better served by a deltopectoral/deltoid-split shoulder exposure; prior anterior surgery with scarred musculocutaneous/lateral antebrachial cutaneous nerves.

Surgical Anatomy

Layered anatomy of the anterior arm
  • Skin & fascia β€” incision over the lateral border of biceps brachii along a line from the coracoid to the lateral epicondyle (or the relevant segment of it).
  • Superficial muscle plane β€” biceps brachii (musculocutaneous nerve) is retracted medially; the dissection is developed along its lateral border.
  • Musculocutaneous nerve β€” lies on the deep (posterior) surface of biceps, between biceps and brachialis; protected by retracting biceps medially as a unit. Its terminal sensory branch, the lateral antebrachial cutaneous nerve, emerges lateral to biceps just proximal to the elbow.
  • Deep muscle β€” brachialis covers the anterior humeral shaft and is split longitudinally; it has dual innervation (musculocutaneous to the medial/larger superficial head, a radial-nerve branch to the inferolateral fibres of the deep head β€” Leonello 2007).
  • Bone β€” the flat anterior surface of the humeral shaft is reached by sweeping the split brachialis medially and laterally subperiosteally.
The radial nerve β€” where it is, and why the split protects it
  • In the mid-shaft, the radial nerve is posterior (in the spiral groove) and is therefore not in the anterior field β€” a key safety advantage of this approach for proximal/middle-third fractures.
  • In the distal third, the nerve has pierced the lateral intermuscular septum (~10 cm proximal to the lateral epicondyle) to enter the anterior compartment, where it lies in the groove between brachialis (medially) and brachioradialis (laterally).
  • Splitting brachialis and leaving its lateral fibres on the bone interposes muscle between the instruments/plate and the radial nerve β€” the nerve is shielded rather than exposed. This is the anatomical basis of the brachialis-splitting approach.

The Approach β€” Step by Step

  • Supine on a radiolucent table with the arm on an arm board or across the chest; a small bump under the scapula assists proximal access. Image intensifier from the head or the contralateral side.
  • Surface landmarks: the coracoid process and deltopectoral groove proximally, the lateral border of biceps brachii in the arm, and the lateral epicondyle distally β€” the full incision lies along the line joining these.
  • Tailor incision length to the fracture: a proximal-third fracture needs the deltopectoral-derived proximal segment; a distal-third fracture needs the brachialis-splitting distal segment; MIPO uses short proximal and distal windows only.

Dangers & How to Avoid Them

Structures at risk

The single most important rule

For any distal extension or distal bicortical screw, treat the radial nerve as present in the field: it has crossed from posterior to anterior through the lateral intermuscular septum in the distal third. Either positively identify it between brachialis and brachioradialis, or keep the lateral brachialis fibres interposed and confirm screw trajectory away from the posterolateral cortex. Most iatrogenic palsies in anterior humeral surgery occur distally.

Anterolateral vs Posterior Approach to the Humeral Shaft

Choosing the approach

Outcomes & Evidence

Evidence

Brachialis is dual-innervated β€” the anatomical basis of the safe split

Anatomical (cadaveric, 11 limbs)
Leonello DT, Galley IJ, Bain GI, Carter CD β€’ Journal of Bone and Joint Surgery (American) (2007)
Evidence

Humeral shaft approaches & MIPO β€” the anterior corridor

Narrative review
Orapiriyakul W, Apivatthakakul V, Theppariyapol B, Apivatthakakul T β€’ Journal of Clinical Orthopaedics and Trauma (2023)
Evidence attribution

Based on articles retrieved from PubMed. The cadaveric innervation data are from Leonello et al. (DOI) and the approach/MIPO synthesis from Orapiriyakul et al. (DOI). The layered anatomy, the deltopectoral proximal extension, and the radial-nerve relationships in the distal third reflect standard, well-established surgical-anatomy teaching (Hoppenfeld/AO descriptions) rather than a single cited trial.

Viva Scenarios

Practise clinical reasoning and management decisions out loud

Viva scenarioStandard
Clinical prompt

β€œYou are plating a middle-third humeral shaft fracture through an anterolateral approach. The examiner asks: 'What is your internervous plane, and is the brachialis split safe?'”

Practical approach
Proximally the internervous plane is the deltopectoral interval (deltoid β€” axillary nerve; pectoralis major β€” pectoral nerves). In the arm there is NO true internervous interval: I develop the approach lateral to biceps, retract biceps and the musculocutaneous nerve medially, and SPLIT the brachialis longitudinally. The split is safe because brachialis is dual-innervated β€” the medial part by the musculocutaneous nerve and the lateral part by a radial-nerve branch (Leonello 2007) β€” so each half keeps its nerve supply, and the lateral fibres left on the bone shield the radial nerve.
Viva scenarioStandard
Clinical prompt

β€œA patient develops a radial nerve palsy after anterior plating of a distal-third humeral shaft fracture. The examiner asks how this approach can injure the radial nerve when 'the nerve is posterior'.”

Practical approach
The radial nerve is posterior only proximally. In the distal third it has pierced the lateral intermuscular septum (~10 cm above the lateral epicondyle) to lie anteriorly between brachialis and brachioradialis β€” exactly where distal dissection and bicortical screws are placed. The injury is typically from distal extension, retractor pressure against the septum, or a posterolaterally directed distal screw. Prevention is to identify or deliberately protect the nerve before distal fixation, keep lateral brachialis fibres interposed, and check screw trajectory.

Viva & Exam Focus

Mnemonic

LARMBrachialis split safety

Hook:Split the brachialis down the middle: Lateral half is Radial, Medial half is Musculocutaneous β€” so each half keeps its nerve and the radial nerve stays cushioned.

High-yield exam points
  • The 'internervous plane' question is a trap β€” name the deltopectoral plane proximally and state plainly that brachialis is SPLIT (dual innervation) distally.
  • The radial nerve is the great danger of the DISTAL extension, not the mid-shaft.
  • This is the corridor for anterior MIPO of the humerus.
Exam day cheat sheet
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