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Polytrauma Management

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Contents
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Polytrauma Management

Comprehensive guide to polytrauma and damage control orthopaedics for FRCS exam preparation

complete
Updated: 2025-12-25

One Page Summary

High Yield Overview

POLYTRAUMA MANAGEMENT

ATLS | Damage Control Orthopaedics | Second Hit

ISS > 15Polytrauma definition
ATLSPrimary survey
DCODamage control orthopaedics
Second HitAvoid with DCO

Patient Categories

Stable
PatternNormal physiology
TreatmentEarly total care (ETC)
Borderline
PatternResponding but vulnerable
TreatmentConsider DCO vs ETC
Unstable
PatternOngoing shock despite resuscitation
TreatmentDCO
In extremis
PatternLife-threatening, dying
TreatmentDCO or damage control surgery

Critical Must-Knows

  • ISS greater than 15 defines polytrauma (major trauma)
  • ATLS primary survey (ABCDE) first
  • Damage control orthopaedics (DCO) for unstable/borderline patients
  • Early total care (ETC) for stable patients
  • Avoid second hit (inflammatory surge from long surgery)

Examiner's Pearls

  • "
    Lethal triad: Hypothermia, acidosis, coagulopathy
  • "
    Borderline patient decision is most challenging
  • "
    Femoral shaft: DCO with external fixator, convert to nail when stable
  • "
    Pelvic binder at greater trochanters

Clinical Imaging

Imaging Gallery

A]Compound Intraarticular fracture of the distal femur. B] Stabilized by a transarticular external fixator. C] Final conversion to the Ilizarov fixator.
Click to expand
A]Compound Intraarticular fracture of the distal femur. B] Stabilized by a transarticular external fixator. C] Final conversion to the Ilizarov fixatoCredit: Dhar SA et al. via J Trauma Manag Outcomes via Open-i (NIH) (Open Access (CC BY))
Type IIIa fracture tibia stabilized by an external fixator. The fracture showed signs of union on return referral whence this treatment modality was continued. The final result shows union.
Click to expand
Type IIIa fracture tibia stabilized by an external fixator. The fracture showed signs of union on return referral whence this treatment modality was cCredit: Dhar SA et al. via J Trauma Manag Outcomes via Open-i (NIH) (Open Access (CC BY))
Type IIIb fracture of the tibia stabilized by an external fixator. The fracture was converted to an interlocking nail and the final result is shown.
Click to expand
Type IIIb fracture of the tibia stabilized by an external fixator. The fracture was converted to an interlocking nail and the final result is shown.Credit: Dhar SA et al. via J Trauma Manag Outcomes via Open-i (NIH) (Open Access (CC BY))
38-year-old male patient after multiple trauma (femoral neck fracture and multi-fragment shaft fracture). Two step stabilization, primarily with external fixator and DHS, secondarily with retrograde n
Click to expand
38-year-old male patient after multiple trauma (femoral neck fracture and multi-fragment shaft fracture). Two step stabilization, primarily with exterCredit: von Rüden C et al. via J Orthop Surg Res via Open-i (NIH) (Open Access (CC BY))

Systematic approach to the multiply injured patient prioritizing life-saving interventions.

Critical Polytrauma Points

ATLS First

Primary survey: Airway, Breathing, Circulation, Disability, Exposure. Life-threatening injuries first. Orthopaedic injuries are addressed after resuscitation.

Lethal Triad

Hypothermia, acidosis, coagulopathy. Self-perpetuating. Warm patient, resuscitate, correct coagulopathy (massive transfusion protocol). Keep surgery short.

DCO vs ETC

DCO: Temporary stabilization (ex-fix). Short surgery. For unstable/borderline. ETC: Definitive fixation within 24h. For stable patients. Reduces pulmonary complications.

Second Hit

Inflammatory surge from major surgery (e.g., long femur nailing) can worsen an already primed patient. DCO avoids this. Convert to definitive fixation when patient stable.

Critical warnings regarding the lethal triad and the balance between DCO and ETC.

At a Glance

StatusDefinitionManagement GoalOrthopaedic Fixation
StableNormal physiologyComplete careEarly Total Care (ETC) - Definitive
BorderlineResponding but fragileProtect physiologyDCO vs ETC (case specific)
UnstableOngoing shockLife over limbDamage Control Orthopaedics (DCO)
In ExtremisDyingSave life onlyLife-saving surgery only

Quick reference table for physiological categorization and management decisions.

Essential Mnemonics

Mnemonic

ABCDEATLS Primary Survey

A
Airway
With C-spine protection
B
Breathing
Ventilation and oxygenation
C
Circulation
Haemorrhage control, resuscitation
D
Disability
Neurological status (GCS)
E
Exposure
Expose and examine, prevent hypothermia

Memory Hook:ABCDE = systematic trauma assessment!

Mnemonic

HACLethal Triad

H
Hypothermia
Core temp less than 35°C - impairs clotting, cardiac function
A
Acidosis
Base deficit greater than 6, lactate greater than 2.5 - tissue hypoperfusion
C
Coagulopathy
Consumption, dilution, hypothermia-induced - causes ongoing bleeding

Memory Hook:HAC the triad - break the cycle or patient dies!

Mnemonic

CRASHDCO Indications

C
Coagulopathy
INR greater than 1.5, ongoing transfusion requirements
R
Respiratory injury
Pulmonary contusion, chest AIS greater than 2
A
Acidosis
Base deficit greater than 8, pH less than 7.25
S
Shock
Persistent hypotension, lactate greater than 2.5
H
Hypothermia
Core temp less than 32°C

Memory Hook:CRASH patients need DCO, not ETC!

Overview

Polytrauma is defined as an ISS (Injury Severity Score) greater than 15, indicating multiple injuries with life-threatening potential. ATLS principles prioritize life-saving interventions via a systematic primary survey.

📊 Management Algorithm
Polytrauma Management Algorithm
Click to expand
Clinical decision-making algorithm for polytrauma: ATLS primary survey (ABCDE) is followed by physiological categorization. Stable patients receive Early Total Care (ETC), while unstable or borderline patients receive Damage Control Orthopaedics (DCO) to avoid the second-hit inflammatory surge.

Epidemiology

  • Incidence: Polytrauma accounts for approximately 25-27% of major trauma admissions (all those with ISS greater than 15). [1,2]
  • Age Distribution:
    • Bimodal peaks: Younger adults (21-30 years) involved in high-energy trauma (RTAs/Falls). [3]
    • Geriatric rise: Increasing prevalence in patients older than 65 years due to low-energy falls in fragile patients with comorbid conditions. [4]
  • Mechanism of Injury:
    • Road Traffic Accidents (RTA): Predominant cause (~65%) in the working-age population. [1,5]
    • Falls from height: Significant contributor to high-energy orthopedic trauma. [5]
  • Mortality: Correlates strongly with ISS; patients with ISS 50-75 face mortality rates exceeding 50%. Geriatric patients have significantly higher mortality for equivalent injury scores. [2,4]

Biomechanics and Physiological Decline

Lethal Triad

Hypothermia, acidosis, coagulopathy. These are inter-related and self-perpetuating. The goal of resuscitation is to break this cycle.

Second Hit Phenomenon

The initial injury causes a systemic inflammatory response (SIRS). A "second hit" from major surgery can overwhelm the patient, leading to ARDS, MODS, and death.

DCO aims to stabilize fractures with minimal physiological insult, avoiding the second hit.

Patient Categories

Based on physiological status, not injury severity alone:

Stable: Normal vital signs, responding to resuscitation, no evidence of ongoing shock. → Early Total Care (ETC).

Borderline: Initially responding but has risk factors (ISS greater than 40, hypothermia, pulmonary injury, bilateral femur fractures, shock with massive transfusion). → Judgment call - DCO or ETC.

Unstable: Persistent shock despite resuscitation, ongoing haemorrhage. → DCO.

In extremis: Dying patient, near arrest, maximal therapy. → Damage control surgery (life-saving).

Orthopaedic Management

Damage Control Orthopaedics

Goal: Rapidly stabilize fractures with minimal physiological insult. Buy time for resuscitation.

Techniques:

  • External fixator for long bone fractures (femur, tibia)
  • Pelvic binder or external fixator for pelvic fractures
  • Splinting for other fractures

Benefits: Short surgery, minimal blood loss, avoids second hit.

Conversion: When patient stable (usually 5-10 days), convert external fixator to definitive fixation (IM nail, ORIF).

Early Total Care

Goal: Definitive fixation within 24 hours.

Patient: Stable, no evidence of physiological derangement.

Evidence: Reduces pulmonary complications, DVT, fat embolism in stable patients. Allows early mobilization.

Typical Scenario: Isolated femur fracture in otherwise healthy patient. Antegrade nailing within 24 hours.

Borderline patient is the challenge.

Factors favoring DCO:

  • ISS greater than 40
  • Hypothermia (less than 35°C)
  • Initial systolic BP less than 90mmHg
  • Coagulopathy
  • Pulmonary injury (pulmonary contusion)
  • Massive transfusion (greater than 10 units PRBC)
  • Lactate greater than 2.5 mmol/L
  • Head injury with intracranial pressure issues

If in doubt: DCO is safer. Can always convert to ETC later.

Resuscitation First

Do not rush to fracture fixation in an unstable patient. Resuscitation and addressing life-threatening injuries takes priority. Orthopaedic DCO is designed to allow life-saving resuscitation to continue.

Anatomy and Pathophysiology

Polytrauma does not have a specific anatomical focus - it involves multiple body regions simultaneously. Key anatomical considerations:

  • Thorax: Rib fractures, flail chest, pulmonary contusion affect respiratory function
  • Abdomen: Solid organ injury (liver, spleen) causes haemorrhage
  • Pelvis: Ring disruption causes major haemorrhage (arterial and venous)
  • Femur: Shaft fractures associated with significant blood loss (1-2 litres per femur)
  • Spine: Associated in up to 10% of major trauma - assume unstable until cleared

Pathophysiology

The Inflammatory Response in Trauma

First Hit (Initial Trauma)

The initial injury triggers a systemic inflammatory response syndrome (SIRS):

  • Tissue damage releases damage-associated molecular patterns (DAMPs)
  • Inflammatory cytokine cascade: IL-1, IL-6, TNF-α released
  • Complement activation and neutrophil priming
  • Endothelial dysfunction and capillary leak
  • The response is proportional to injury severity (ISS)

Second Hit Phenomenon

Additional surgical insult during the inflammatory phase amplifies SIRS:

  • Prolonged surgery (greater than 2 hours) acts as a "second hit"
  • Reaming of long bones releases fat, marrow, cytokines
  • Can precipitate multi-organ dysfunction syndrome (MODS)
  • ARDS, acute kidney injury, coagulopathy may develop

DCO Rationale

Damage control orthopaedics minimises the second hit by:

  • Temporary external fixation (minimal additional trauma)
  • Delayed definitive surgery when inflammation has resolved (5-10 days)
  • Monitoring inflammatory markers (CRP, IL-6) to guide timing
  • The "window of opportunity" for conversion is days 5-10 post-injury

Classification

Injury Severity Scoring Systems

Injury Severity Score (ISS):

  • Most widely used trauma scoring system
  • Sum of squares of AIS (Abbreviated Injury Scale) for 3 most injured body regions
  • Range 1-75 (AIS 6 in any region = ISS 75 automatically)
  • ISS greater than 15 = major trauma (polytrauma)
  • ISS greater than 25 = severe trauma
  • ISS greater than 40 = critical, high mortality

New Injury Severity Score (NISS):

  • Sum of squares of 3 highest AIS scores regardless of body region
  • May better predict mortality in certain injury patterns
  • Particularly useful when multiple injuries in same body region

Patient Physiological Categories:

CategoryDefinitionManagement
StableNormal vitals, responding to resuscitationETC appropriate
BorderlineResponding but has risk factorsDCO vs ETC - judgment call
UnstablePersistent shock despite resuscitationDCO
In ExtremisDying, near arrestLife-saving surgery only

Advanced Scoring Systems

AIS (Abbreviated Injury Scale):

  • 1 = Minor, 2 = Moderate, 3 = Serious
  • 4 = Severe, 5 = Critical, 6 = Unsurvivable

Body Regions for ISS:

  • Head/Neck, Face, Chest, Abdomen, Extremities, External

Trauma and Injury Severity Score (TRISS):

  • Combines anatomic (ISS) and physiologic (RTS) parameters
  • Predicts probability of survival
  • Used for trauma registry quality assessment

ISS Calculation

**ISS = (highest AIS)² + (2nd highest AIS)² + (3rd highest AIS)**². Only one injury per body region counted. Example: Head AIS 4 + Chest AIS 3 + Extremity AIS 3 = 16 + 9 + 9 = ISS 34 (severe polytrauma).

Clinical Assessment

ATLS Primary Survey (ABCDE)

A - Airway with C-spine Protection:

  • Chin lift/jaw thrust (avoid head tilt in trauma)
  • Clear debris, suction, insert airway adjunct
  • Definitive airway if GCS less than 8 or cannot protect airway
  • Maintain in-line immobilization during intubation

B - Breathing and Ventilation:

  • Expose chest, assess respiratory rate and effort
  • Life-threatening chest injuries: tension pneumothorax, open pneumothorax, massive haemothorax, flail chest with pulmonary contusion
  • Needle decompression or chest tube as indicated

C - Circulation with Haemorrhage Control:

  • Assess pulse, BP, capillary refill, skin color
  • IV access (2 large bore), initiate fluid resuscitation
  • Apply direct pressure to external bleeding
  • Pelvic binder if suspected pelvic ring injury
  • Initiate massive transfusion protocol if indicated

D - Disability (Neurological):

  • GCS assessment
  • Pupillary response
  • Gross motor function

E - Exposure with Environmental Control:

  • Fully undress patient for complete examination
  • Log roll for back and spine examination
  • Actively prevent hypothermia (warm blankets, fluid warmers)

The primary survey must be completed and life-threatening injuries addressed before fracture care.

Secondary Survey and Monitoring

Secondary Survey:

  • Complete head-to-toe examination once patient stabilized
  • AMPLE history: Allergies, Medications, Past history, Last meal, Events
  • Detailed neurological examination
  • Complete musculoskeletal examination (all joints, spine)

Physiological Monitoring Parameters:

  • Base excess: Target greater than -6 mmol/L
  • Lactate: Target less than 2.5 mmol/L (tissue perfusion marker)
  • Temperature: Prevent less than 35°C
  • Coagulation: INR, fibrinogen, platelets
  • Urine output: Target greater than 0.5 mL/kg/hr

Clinical Assessment Pitfalls

Missed injuries common in polytrauma: C-spine (10% miss rate with XR alone), extremity fractures in intubated patients, posterior injuries (spine, pelvis), vascular injuries. Always log roll. Tertiary survey at 24-48 hours catches up to 10% of missed injuries.

Investigations

Initial Trauma Investigations

Laboratory Studies:

  • Blood gas: pH, base excess, lactate - assess tissue perfusion
  • FBC: Haemoglobin (often normal initially despite blood loss)
  • Coagulation: PT/INR, APTT, fibrinogen - guide transfusion
  • Cross-match: Urgent type and screen, O-negative if exsanguinating
  • TEG/ROTEM: Point-of-care coagulation assessment if available

Imaging - Primary Survey:

  • CXR portable: Pneumothorax, haemothorax, widened mediastinum
  • Pelvic XR: Pelvic ring disruption
  • FAST scan: Free fluid in abdomen/pericardium

CT Imaging (once stable):

  • CT Head: Intracranial haemorrhage, midline shift
  • CT Chest/Abdomen/Pelvis: Solid organ injury, aortic injury, spine fractures
  • Whole-body CT (pan-scan): Standard in major trauma centers for ISS greater than 15

Pan-scan is the gold standard for rapid injury assessment once hemodynamically stabilized.

Advanced Trauma Imaging

Orthopaedic-Specific Imaging:

  • Long bone X-rays once patient stabilized
  • CT spine (C-spine, thoracolumbar if indicated)
  • CT pelvis 3D reconstruction for complex pelvic ring injuries
  • CT angiography if vascular injury suspected

Physiological Markers for DCO Decision:

ParameterDCO ThresholdSignificance
Base excessLess than -6 to -8 mmol/LTissue hypoperfusion
LactateGreater than 2.5-4 mmol/LAnaerobic metabolism
TemperatureLess than 35°CImpaired coagulation
INRGreater than 1.5Coagulopathy
TransfusionGreater than 10 units PRBCMassive blood loss
pHLess than 7.25Severe acidosis

Pan-Scan Protocol

Whole-body CT (head to pelvis with IV contrast) is now standard for major trauma (ISS greater than 15) in Australian trauma centers. Reduces missed injury rate, faster than sequential imaging, and allows early operative planning. Perform after primary survey and initial stabilization.

Management Algorithm

Polytrauma Management Algorithm

Phase 1: Resuscitation (0-24 hours)

  • ATLS primary survey and resuscitation
  • Life-saving surgery (laparotomy, thoracotomy, craniotomy)
  • Massive transfusion protocol if indicated
  • Pelvic binder, external fixation for pelvis
  • Orthopaedic DCO or ETC decision

Phase 2: Stabilization (24-72 hours)

  • ICU care: ventilation, organ support
  • Correction of lethal triad
  • Serial lactate and base excess monitoring
  • Reassessment of orthopaedic injuries
  • Secondary and tertiary surveys

Phase 3: Definitive Care (Day 5-10)

  • Conversion of external fixators to definitive fixation
  • Scheduled orthopaedic procedures
  • Monitor inflammatory markers (CRP, IL-6) before surgery

Massive Transfusion Protocol (MTP):

  • 1:1:1 ratio PRBC:FFP:Platelets
  • Tranexamic acid within 3 hours of injury
  • Fibrinogen supplementation (target greater than 1.5 g/L)
  • Calcium replacement with every 4 units blood

Resuscitation must balance hemodynamics with physiological stability.

Decision-Making for Borderline Patients

DCO Indications (Choose DCO if ANY present):

  • ISS greater than 40
  • ISS greater than 20 with thoracic injury (AIS greater than 2)
  • Bilateral femur fractures with shock
  • Hypothermia less than 32°C
  • Base deficit greater than 8
  • Pulmonary contusion on CT
  • Ongoing transfusion (greater than 10 units)
  • Raised intracranial pressure

ETC Indications:

  • Isolated extremity fractures
  • Stable vital signs throughout resuscitation
  • No chest injury
  • Lactate normalizing
  • No coagulopathy

Conversion Timing (Ex-fix to Nail):

  • Patient stable off vasopressors
  • Lactate normalized
  • Temperature greater than 36°C
  • Coagulation corrected
  • CRP trending down (usually day 5-10)
  • Pin sites clean (no infection)

Pin Site Infection Risk

External fixator pin site infection increases deep infection risk when converting to intramedullary nailing. If pin sites infected, consider: (1) Different entry point for nail, (2) Staged procedure with antibiotic spacer, (3) Plate fixation avoiding pin sites. Standard recommendation: convert within 2 weeks before biofilm formation.

Surgical Technique

DCO Techniques by Fracture Location

Femoral Shaft:

  • Spanning external fixator (hip to knee or knee-sparing)
  • Pins: 2 proximal (subtrochanteric), 2 distal (supracondylar)
  • Restore length and alignment
  • Convert to antegrade IM nail when stable

Tibial Shaft:

  • Spanning external fixator or immediate IM nailing (less physiological insult than femur nailing)
  • Pins: 2 proximal (metaphyseal), 2 distal (metaphyseal)
  • Tibial nailing can often proceed even in borderline patients

Pelvis:

  • Pelvic binder first (at greater trochanters, NOT iliac crests)
  • C-clamp for posterior ring if hemodynamically unstable
  • Anterior external fixator (supra-acetabular pins or iliac crest pins)
  • Angiography and embolization if ongoing arterial bleeding

Open Fractures:

  • Debridement and washout
  • Temporary external fixation
  • Delayed soft tissue coverage and conversion to internal fixation

Temporary stabilization is critical in the early phase of open fracture management.

Specific DCO Constructs

Femoral External Fixator Construct:

  • 5mm half-pins
  • Proximal pins: Anterolateral approach, avoid femoral vessels
  • Distal pins: Lateral supracondylar, avoid knee joint
  • Frame configuration: Single bar or delta frame for stability
  • Key: Restore length and alignment for easier conversion

Pelvic Fixation Options:

TechniqueIndicationAdvantage
Pelvic binderInitial stabilizationNon-invasive, immediate
Anterior ex-fixOpen book injuryRapid, controls anterior ring
C-clampPosterior ring instabilityPosterior compression
Retrograde ISSDefinitive fixationMinimally invasive if stable

Nailing Considerations in Polytrauma:

  • Unreamed nailing may reduce pulmonary insult (controversial)
  • Femoral nailing causes more fat embolism than tibial nailing
  • Vented nailing technique to reduce intramedullary pressure
  • Consider damage control nailing (nail without final fixation)

Ex-Fix to Nail Conversion

Convert external fixator to IM nail within 2 weeks to minimize pin tract infection risk. If pin sites infected: change entry point, consider staged procedure with antibiotic cement, or use plate fixation avoiding pin sites. Deep infection rate increases from 2% to 10-15% if pin sites colonized.

Complications

Polytrauma Complications

Early Complications (0-72 hours):

  • Haemorrhagic shock: Ongoing blood loss, coagulopathy
  • ARDS: Pulmonary contusion, fat embolism, transfusion-related
  • Compartment syndrome: High index of suspicion in unconscious patients
  • Missed injuries: Up to 10% detected on tertiary survey
  • Fat embolism syndrome: Triad of hypoxia, confusion, petechiae

Late Complications (Days to weeks):

  • Multi-organ dysfunction syndrome (MODS): Inflammatory cascade
  • Sepsis: Nosocomial infection, open fractures
  • VTE: High risk in immobile polytrauma patients
  • Nonunion/malunion: Inadequate initial stabilization
  • Heterotopic ossification: Common in head injury + extremity fracture

Orthopaedic-Specific Complications:

  • Pin site infection (5-10% with ex-fix)
  • Deep infection after conversion (2-15% depending on pin status)
  • Nonunion (higher in delayed treatment)
  • Stiffness (prolonged immobilization)

Vigilant monitoring for metabolic and pulmonary complications is essential.

Prevention and Management

ARDS Prevention:

  • Early stabilization of long bone fractures (reduces pulmonary emboli)
  • Avoid fluid overload
  • Lung-protective ventilation
  • DCO in high-risk patients avoids second hit

Fat Embolism Syndrome:

  • Incidence 1-10% in long bone fractures
  • Mechanical theory: fat from medullary canal enters circulation
  • Biochemical theory: inflammatory response to circulating fat
  • Prevention: Early fracture stabilization, avoid hypoxia
  • Treatment: Supportive (oxygen, ventilation), no specific therapy

VTE Prophylaxis:

  • Mechanical: SCDs, IPC from admission
  • Pharmacological: LMWH when bleeding risk acceptable (usually 24-48 hours post-injury)
  • Duration: Until mobile, typically 2-4 weeks
  • IVC filter considered if anticoagulation contraindicated

Missed Injury Prevention

Tertiary survey at 24-48 hours is mandatory in polytrauma. Patient awake and cooperative allows better examination. Up to 10% of injuries missed on initial survey. Repeat imaging if new symptoms emerge. Document all injuries in trauma registry.

Postoperative Care

ICU Phase Management

Ongoing Resuscitation:

  • Goal-directed therapy: lactate clearance, urine output
  • Blood product replacement per MTP
  • Temperature management (active warming to greater than 36°C)
  • Nutrition: early enteral feeding when possible

Monitoring:

  • Serial lactate and base excess
  • Daily bloods: FBC, coagulation, renal function
  • CRP and inflammatory markers for conversion timing
  • Compartment checks in sedated patients

DVT Prophylaxis:

  • Mechanical (SCDs/IPC) from admission

  • Pharmacological once bleeding risk acceptable

  • Enoxaparin 40mg daily or equivalent

  • Plan for conversion to definitive fixation

Conversion criteria should be strictly followed to avoid complications.

Conversion Planning and Rehabilitation

Conversion Criteria (Ex-fix to Definitive):

  • Hemodynamically stable, off vasopressors
  • Lactate less than 2.5 mmol/L
  • Temperature greater than 36°C
  • No coagulopathy
  • CRP decreasing
  • No active infection
  • Usually day 5-10 post-injury

Early Mobilization:

  • Passive ROM when stable
  • Chest physiotherapy critical
  • Early weight bearing per fracture pattern
  • Psychological support (PTSD screening)

Long-term Rehabilitation:

  • Multidisciplinary team approach
  • Physical therapy program
  • Occupational therapy for ADL retraining
  • Chronic pain management
  • Return to work assessment

Early vs Delayed Conversion

Convert ex-fix to IM nail within 2 weeks ideally. Earlier conversion (day 5-7) has lower infection rates than later conversion (greater than 2 weeks). Pin sites should be clean. If signs of infection, consider alternative fixation avoiding pin sites or staged procedure.

Outcomes

Polytrauma Survival Outcomes

Mortality Rates by ISS:

  • ISS 16-24: 5-10% mortality
  • ISS 25-40: 15-25% mortality
  • ISS greater than 40: 30-50% mortality
  • ISS 75: Near 100% mortality

Factors Affecting Mortality:

  • Age (mortality increases significantly over 65)

  • Injury pattern (head + chest worst prognosis)

  • Time to definitive care

  • Trauma center volume and resources

  • Comorbidities

  • Inappropriate ETC in unstable patient increases MODS risk

Proper patient selection is the most critical factor in survival outcomes.

Functional Outcomes

Return to Work:

  • ISS 16-24: 70-80% return to previous occupation
  • ISS 25-40: 50-60% return to work
  • ISS greater than 40: Often permanent disability

Quality of Life:

  • Physical function most affected
  • Psychological sequelae common (PTSD 20-40%)
  • Chronic pain in 30-50%
  • Cognitive impairment if significant head injury

Orthopaedic-Specific Outcomes:

  • Fracture healing: Generally good with appropriate treatment
  • Nonunion rate: 5-10% for long bones (higher with open fractures)
  • Functional outcomes: Dependent on associated injuries, not just fracture

Evidence for DCO

Key evidence: Pape et al. landmark studies showed that unstable/borderline polytrauma patients benefit from DCO with external fixation followed by delayed nailing. ARDS rate reduced. However, stable patients benefit from ETC (early nailing within 24h) with reduced pulmonary complications and shorter hospital stay.

Evidence Base

Key Evidence for Polytrauma Management

Early Total Care (ETC) Evidence:

  • Bone et al. (1989): Landmark study showing early femoral stabilization (less than 24h) reduces ARDS, fat embolism, and hospital stay in stable patients
  • Multiple subsequent studies confirmed benefit of early long bone fixation in stable patients

Damage Control Orthopaedics (DCO) Evidence:

  • Pape et al. (2002): Defined DCO concept - external fixation for unstable patients avoids second hit

  • Scalea et al. (2000): Showed DCO reduces pulmonary complications in borderline patients

  • Conversion timing: Days 5-10 optimal (Pape et al.)

  • CRASH-2 Trial (2010): Tranexamic acid within 3 hours reduces mortality

Evidence-based protocols focus on physiological optimization and balanced resuscitation.

Advanced Evidence and Guidelines

Key Studies:

StudyYearKey Finding
Bone (JBJS)1989Early femur fixation reduces ARDS
Pape (J Trauma)2002DCO concept for borderline patients
Scalea (J Trauma)2000DCO reduces second hit
PROPPR20151:1:1 transfusion ratio
CRASH-22010TXA within 3h saves lives

Current Guidelines:

  • ATLS guidelines: Primary and secondary survey principles
  • EAST guidelines: Early femur fixation when appropriate
  • Orthopaedic Trauma Association: DCO vs ETC decision framework

Controversies:

  • Exact thresholds for borderline patient remain debated
  • Reamed vs unreamed nailing in polytrauma
  • Role of early total care in modern trauma systems

Landmark ETC Study

Level I
Bone LB, Johnson KD, Weigelt J, Scheinberg R
📚 Bone LB et al. JBJS 1989
Key Findings:
  • Prospective randomized study of 178 patients with femoral fractures.
  • Early fixation (less than 24h) significantly reduced pulmonary complications (ARDS, Fat Embolism).
  • Mean hospital stay reduced from 15.8 to 11.2 days.
  • Conclusion: Stable polytrauma patients benefit from early definitive stabilization.

Evolution of DCO concept

Level III
Pape HC, Hildebrand F, Pertschy S, et al.
📚 Pape HC et al. Journal of Trauma 2002
Key Findings:
  • Compared early total care (ETC) vs damage control orthopaedics (DCO) in 369 borderline patients.
  • DCO (external fixation) reduced the rate of post-traumatic ARDS and Multi-Organ Failure (MOF).
  • Introduction of the 'Second Hit' hypothesis: surgical stress can amplify the initial inflammatory response.
  • Reduction in overall mortality and systemic complications in borderline categories.

Massive Transfusion (1:1:1)

Level I
Holcomb JB, Tilley BC, Baraniuk S, et al.
📚 PROPPR Trial. JAMA 2015
Key Findings:
  • Randomized trial of 680 severely injured patients with major hemorrhage.
  • Compared 1:1:1 vs 1:1:2 ratios (Plasma:Platelets:PRBC).
  • 1:1:1 group achieved better hemostasis and fewer deaths from exsanguination in the first 24 hours.
  • No significant difference in overall 30-day mortality but clear benefit in early survivability.

Tranexamic Acid in Trauma

Level I
CRASH-2 collaborators
📚 CRASH-2 Trial. Lancet 2010
Key Findings:
  • Large RCT of 20,211 trauma patients with significant hemorrhage.
  • TXA significantly reduced all-cause mortality (14.5% vs 16.0%).
  • Benefit most pronounced when given within 1 hour of injury.
  • No increase in thrombotic complications (DVT/PE).

Early High-Ratio Transfusion

Level II
Holcomb JB et al.
📚 PROMMTT Study. JAMA Surgery 2013
Key Findings:
  • Prospective observational study of 1,245 trauma patients.
  • Higher ratios of plasma and platelets to PRBCs were associated with decreased mortality in the first 6 hours.
  • Supports 'balanced' resuscitation starting as early as possible.
  • Helped bridge the gap before the PROPPR RCT.

Evidence supports the early administration of TXA in major trauma patients.

Exam Viva Scenarios

Practice these scenarios to excel in your viva examination

VIVA SCENARIOAdvanced

Scenario 1: Polytrauma

EXAMINER

"A motorcyclist arrives with bilateral femoral shaft fractures, pulmonary contusion, and initial BP 80/50. He has received 6 units of blood and now has BP 100/60. How do you manage his femoral fractures?"

EXCEPTIONAL ANSWER
This is a **polytrauma patient** (likely ISS greater than 15 given bilateral femur fractures and pulmonary contusion). He presented in shock (BP 80/50) and has required massive transfusion (6 units so far). He is currently responding to resuscitation (BP 100/60) but remains at high risk. I would categorize him as **borderline** or possibly **unstable**. The key decision is whether to proceed with early total care (ETC, i.e., definitive nailing of both femurs now) or damage control orthopaedics (DCO). Given the multiple risk factors - bilateral femur fractures (significant blood loss ongoing), pulmonary contusion (at risk of ARDS), initial shock, and massive transfusion - I am concerned about the **second hit phenomenon**. Prolonged surgery for bilateral femur nailing could trigger a further inflammatory surge, pushing him into ARDS and multi-organ failure. My decision would be **DCO**. I would apply **external fixators** to both femurs. This is a short procedure that provides stability, controls ongoing bleeding from fractures, allows nursing care, and enables continued resuscitation. The patient would then go to ICU for further resuscitation, rewarming, correction of coagulopathy and acidosis, and monitoring of pulmonary function. When the patient is **physiologically stable** (usually 5-10 days, when lactate normalized, temperature normal, off vasopressors, pulmonary status stable), I would **convert to definitive fixation** with antegrade intramedullary nailing of both femurs.
KEY POINTS TO SCORE
Borderline patient with multiple risk factors
Second hit from long surgery could worsen
DCO: External fixators to both femurs
Convert to nailing when stable
COMMON TRAPS
✗Proceeding with ETC in unstable patient
✗Not recognizing borderline physiology
✗Delaying fracture stabilization entirely
LIKELY FOLLOW-UPS
"What is the lethal triad?"
"When would you convert to definitive fixation?"
VIVA SCENARIOStandard

Scenario 2: Unstable Pelvic Fracture

EXAMINER

"A 45-year-old male is brought in after a high-speed RTA. He is hemodynamically unstable (BP 70/40) with obvious pelvic deformity after an APC-III type injury. How do you proceed?"

EXCEPTIONAL ANSWER
This is an **unstable pelvic ring injury** in a patient with life-threatening hemodynamic instability. Following ATLS protocols, my immediate goal is **circulatory resuscitation and hemorrhage control**. I would immediately apply a **pelvic binder** centered over the greater trochanters. This reduces the pelvic volume and provides a tamponade effect for venous and cancellous bleeding. I would initiate a **Massive Transfusion Protocol (MTP)** and administer **TXA** (within 3 hours). If the patient remains unstable despite these measures and a FAST scan shows no intraperitoneal fluid, I would suspect arterial pelvic bleeding and proceed to the interventional radiology suite for **angiography and embolization**. For the orthopaedic stabilization, if the binder is insufficient, I would apply a **supra-acetabular external fixator** or a **pelvic C-clamp** (if the injury pattern permits) as a part of a damage control strategy. Once the patient's physiology is stabilized in the ICU, I would plan for definitive internal fixation of the pelvic ring.
KEY POINTS TO SCORE
Immediate pelvic binder placement
Massive Transfusion Protocol and TXA
DCO via external fixation or C-clamp
Angiography/embolization for persistent instability
COMMON TRAPS
✗Placing the pelvic binder over the iliac crests
✗Delaying stabilization for definitive CT imaging
✗Ignoring the lethal triad in the resuscitation phase
LIKELY FOLLOW-UPS
"What are the indications for a pelvic C-clamp?"
"When would you convert from DCO to definitive ORIF?"
VIVA SCENARIOModerate

Scenario 3: Stable Polytrauma

EXAMINER

"A 19-year-old female presents with a closed femoral shaft fracture and a minor chest injury (RIB AIS 1). She is hemodynamically stable, lactate 1.2, and pH 7.4. What is your management plan?"

EXCEPTIONAL ANSWER
This patient is a **stable polytrauma patient** despite her injuries. Her physiological markers are normal (lactate 1.2, pH 7.4), and her respiratory status is not significantly compromised by the minor rib injury. According to the principles established by the **Bone study (1989)** and subsequent evidence, she is an ideal candidate for **Early Total Care (ETC)**. I would proceed with **definitive internal fixation** of her femoral shaft fracture, likely with a reamed antegrade intramedullary nail, within the first 24 hours. Definitive stabilization in this timeframe for a stable patient has been shown to **reduce pulmonary complications**, decrease ICU and hospital length of stay, and allow for early mobilization. I would ensure she receives adequate VTE prophylaxis postoperatively.
KEY POINTS TO SCORE
Physiologically stable patient
ETC (Early Total Care) is appropriate
Definitive fixation (nailing) within 24 hours
Reduces ARDS and hospital stay
COMMON TRAPS
✗Using DCO (ex-fix) unnecessarily in a stable patient
✗Delaying fixation beyond 24 hours without physiological reason
✗Ignoring VTE prophylaxis in polytrauma
LIKELY FOLLOW-UPS
"What defines a borderline patient?"
"What are the benefits of reamed vs unreamed nailing?"

MCQ Practice Points

DCO vs ETC

Q: When should damage control orthopaedics (DCO) be used instead of early total care (ETC)?

A: DCO indicated: ISS greater than 40, ISS greater than 20 with additional thoracic injury (AIS greater than 2), bilateral femur fractures with shock, hypothermia less than 32°C, base deficit greater than 8, coagulopathy, ongoing transfusion requirements. ETC appropriate: Borderline patients stabilised by resuscitation, no chest trauma, ISS less than 20.

Second Hit Phenomenon

Q: What is the second hit phenomenon and how does DCO prevent it?

A: The first hit is the initial traumatic insult causing SIRS. The second hit is additional surgical trauma (e.g., prolonged orthopaedic surgery) that amplifies inflammation and can precipitate multi-organ dysfunction syndrome (MODS). DCO prevents this by using temporary stabilisation (external fixation) to minimise surgical stress during the inflammatory phase, with definitive fixation delayed 5-10 days when the patient is optimised.

Femur Fracture Timing

Q: What is the optimal timing for femur fracture fixation in polytrauma?

A: In stable patients, early intramedullary nailing (within 24 hours) reduces pulmonary complications, ICU stay, and hospital stay. In unstable patients (shock, coagulopathy, base deficit greater than 6), use external fixation initially with conversion to IM nail at 5-10 days when inflammatory markers normalise and patient is optimised.

Fat Embolism Prevention

Q: How do you minimise fat embolism risk during IM nailing in polytrauma?

A: Techniques include: reaming cautiously or use unreamed nails in chest trauma, venting the femur during nailing, avoiding over-pressurisation of the canal, surgical stabilisation early (prevents ongoing marrow extravasation from mobile fracture). Monitor for fat embolism syndrome: petechial rash, hypoxia, confusion (classic triad).

Australian Context

Trauma System Organisation

Major Trauma Centres: Australian major trauma centres (MTC) in each state are designated for ISS greater than 15 polytrauma. Victorian State Trauma System, NSW Trauma Network, Queensland Trauma System have established retrieval and transfer protocols.

Retrieval Services: Adult Retrieval Victoria (ARV), CareFlight, RFDS, LifeFlight provide critical care retrieval for rural trauma with direct communication with receiving trauma team.

eTG Antibiotic Guidelines

For open fractures in polytrauma:

  • Type I-II: Cefazolin 2g IV 8-hourly
  • Type III/Contaminated: Add gentamicin 5mg/kg IV daily
  • Farm contamination: Add benzylpenicillin 1.8g IV 6-hourly

RACS Requirements

Trauma Fellowship: RACS offers Trauma Fellowship training with rotations through major trauma centres. FRACS candidates expected to demonstrate DCO principles and polytrauma management competencies.

TPOD (Trauma Plan of the Day): Many Australian hospitals use standardised trauma handover and planning frameworks.

POLYTRAUMA MANAGEMENT

High-Yield Exam Summary

ATLS

  • •ABCDE primary survey
  • •Life-threatening injuries first
  • •Resuscitate before fracture care

Lethal Triad

  • •Hypothermia
  • •Acidosis
  • •Coagulopathy

DCO vs ETC

  • •Stable → ETC (within 24h)
  • •Borderline/Unstable → DCO (ex-fix)
  • •In extremis → Life-saving surgery only

DCO Technique

  • •External fixators for long bones
  • •Pelvic binder for pelvis
  • •Short surgery, minimal blood loss
Quick Stats
Reading Time98 min
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FRACS Guidelines

Australia & New Zealand
  • ACSQHC Trauma Standards
  • RACS Trauma Guidelines
Related Topics

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Basicervical Fractures

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Calcaneal Tuberosity Fractures