SHOULDER ARTHROPLASTY COMPLICATIONS
High Revision Rates | Glenoid Loosening | Instability Risk | Infection Management
MAJOR COMPLICATIONS
Critical Must-Knows
- Glenoid loosening is the leading cause of failure in anatomic TSA (20-30% radiolucency at 10 years)
- Instability is the most common complication of RSA (5-10%), often requiring revision
- Axillary nerve at highest risk during deltopectoral approach - check function preop and postop
- Infection requires minimum 6 weeks IV antibiotics; single-stage revision controversial
- Subscapularis failure leads to anterior instability - repair integrity critical in anatomic TSA
Examiner's Pearls
- "Glenoid baseplate failure in RSA often related to poor bone stock or scapular notching
- "Periprosthetic fractures classified by Vancouver system (adapted for shoulder)
- "Staphylococcus epidermidis most common organism in shoulder PJI
- "Notching occurs in up to 70% of RSA but clinically significant in less than 10%
Clinical Imaging
Imaging Gallery
Critical Shoulder Arthroplasty Complications Exam Points
Glenoid Loosening
Leading cause of TSA failure. Radiolucent lines in Lazarus zones, eccentric glenoid wear, rocking horse phenomenon. Revision requires bone grafting in 30-50% of cases.
Instability Patterns
RSA: posterior (60%), anterior (30%). TSA: anterior from subscapularis failure. Risk factors: poor component positioning, tissue deficiency, trauma. May require constraint or revision.
Infection Recognition
2-6% incidence, higher in revision. Propionibacterium acnes (indolent), S. epidermidis (acute). Hold sonication cultures 14 days. Biofilm on components requires removal.
Nerve Injuries
Axillary nerve most common (1-4%). Also musculocutaneous, suprascapular. Most are neurapraxias recovering in 3-6 months. EMG at 3-4 weeks if no recovery. Document preop function.
Quick Complication Management Guide
| Complication | Timing | Key Features | Management |
|---|---|---|---|
| Acute infection | Less than 4 weeks postop | Wound drainage, fever, elevated CRP | Debridement, polyethylene exchange, long-term antibiotics |
| Instability (RSA) | Early (less than 3 months) | Posterior in 60%, traumatic or atraumatic | Closed reduction, assess component position, revise if malpositioned |
| Glenoid loosening (TSA) | Late (over 5 years) | Pain, crepitus, radiolucent lines | Revision TSA or convert to RSA depending on rotator cuff |
| Nerve injury | Immediate postop | Deltoid weakness (axillary), sensory loss | Observation for 3-6 months, EMG at 3-4 weeks, exploration if no recovery |
Mnemonic Aids
At a Glance
Shoulder arthroplasty complications have an overall rate of 10-15%. Glenoid loosening is the leading cause of anatomic TSA failure, with radiolucent lines (Lazarus zones) developing in 20-30% at 10 years. Instability is the most common complication of reverse shoulder arthroplasty (RSA) at 5-10%, typically posterior (60%) and often requiring revision. The axillary nerve is the nerve most at risk (1-4% injury rate), with most injuries being neurapraxias that recover in 3-6 months. Infection rates are 2-6%; Propionibacterium acnes (indolent) and Staphylococcus epidermidis (acute) are the most common organisms—hold cultures for 14 days and remove components for biofilm eradication. Scapular notching occurs in up to 70% of RSA but is clinically significant in under 10%.
INGLEMajor Shoulder Arthroplasty Complications
Memory Hook:INGLE = IN GLE-noid we trust, but complications happen: Instability, Nerve, Glenoid, Loosening, infEction!
STORMRisk Factors for Instability After RSA
Memory Hook:STORM = after RSA, these factors create a STORM of instability risk!
LAZARUSGlenoid Radiolucent Line Zones (Lazarus Classification)
Memory Hook:LAZARUS = like Lazarus rising from the dead, glenoid lucent lines signal implant death approaching!
Overview and Epidemiology
Why Complications Matter in Shoulder Arthroplasty
Shoulder arthroplasty has the highest revision rate of all joint replacements (approximately 10% at 10 years for TSA, 15% for RSA). Understanding complication patterns, recognition, and management is critical for exam success and patient care. Registry data shows complication rates increasing with time, making long-term surveillance essential.
Complication Timing
- Early (less than 3 months): Infection, nerve injury, instability, fracture
- Intermediate (3 months - 2 years): Periprosthetic fracture, component loosening
- Late (over 2 years): Glenoid wear, osteolysis, subscapularis failure, cuff tear
- Any time: Instability can occur early or late
Impact on Outcomes
- Revision surgery: 2-3x higher complication rate than primary
- Functional loss: 20-30 point drop in outcome scores after complication
- Patient satisfaction: Drops from 90% to under 60% with major complication
- Healthcare costs: Revision procedures cost 2-3x primary arthroplasty
Pathophysiology of Complications
Understanding Complication Mechanisms
Shoulder arthroplasty complications arise from three main pathophysiologic mechanisms: biological (infection, bone resorption, soft tissue failure), mechanical (instability, component loosening, wear), and technical (malposition, sizing errors, nerve injury). Understanding these mechanisms guides both prevention and treatment strategies.
Biological Mechanisms
- Infection: Biofilm formation on implant surfaces (S. epidermidis, P. acnes)
- Osteolysis: Polyethylene wear debris triggers macrophage activation
- Bone resorption: Stress shielding from humeral stem, glenoid bone loss
- Soft tissue failure: Subscapularis repair failure, rotator cuff progression
Mechanical Mechanisms
- Instability: Insufficient soft tissue tension, component malposition
- Glenoid loosening: Eccentric loading (rocking horse), poor fixation
- Impingement: Scapular notching in RSA, subacromial in TSA
- Wear: Metal-on-polyethylene articulation over time
Pathophysiology by Complication Type
| Complication | Primary Mechanism | Contributing Factors | Time Course |
|---|---|---|---|
| Acute infection | Bacterial contamination and biofilm | S. aureus most common, surgical factors, patient comorbidities | Less than 4 weeks postoperative |
| Chronic infection | Indolent bacterial colonization | P. acnes biofilm, male patients, low virulence organisms | Over 3 months, often years |
| Instability (RSA) | Loss of soft tissue tension | Insufficient lateralization, component malposition, subscapularis deficiency | Early (less than 3 months) or late (after trauma) |
| Glenoid loosening (TSA) | Eccentric loading and micromotion | Rocking horse phenomenon, poor cement technique, young active patient | Progressive over 5-10 years |
| Nerve injury | Traction or direct trauma | Retractor pressure, arm positioning, anatomic proximity | Immediate intraoperative |
The Rocking Horse Phenomenon
Eccentric glenoid loading in anatomic TSA creates asymmetric forces on the glenoid component with arm elevation. Superior loading during elevation causes the humeral head to act as a fulcrum, rocking the glenoid component. This micromotion disrupts the cement-bone interface, leading to radiolucent lines and progressive loosening. Prevention requires optimal component positioning, cement pressurization, and patient selection.
Classification of Complications
Temporal Classification
| Phase | Complications | Incidence | Key Management |
|---|---|---|---|
| Immediate (less than 2 weeks) | Nerve injury, acute infection, dislocation | 5-8% combined | Early recognition, urgent intervention for infection |
| Early (2 weeks - 3 months) | Instability, periprosthetic fracture, wound issues | 3-5% | Component assessment, revision if malpositioning |
| Intermediate (3 months - 2 years) | Aseptic loosening, late infection, subscapularis failure | 5-10% | Imaging surveillance, functional assessment |
| Late (over 2 years) | Component wear, osteolysis, cuff tears, scapular notching | 15-20% by 10 years | Monitor, revise when symptomatic or progressive |
Timing Pattern Recognition
Acute pain and fever within first month = infection until proven otherwise. Sudden loss of function after minor trauma = consider instability or periprosthetic fracture. Progressive pain over months = consider component loosening. Timing is key to differential diagnosis.
Clinical Presentation
Clinical Features by Complication Type
| Complication | Pain Pattern | Functional Loss | Physical Findings |
|---|---|---|---|
| Acute infection | Constant, severe, worse at night | Significant loss of function, unwilling to move | Fever, wound drainage, erythema, warmth, tenderness |
| Chronic infection (P. acnes) | Persistent ache, not severe | Moderate limitation, gradual decline | Minimal external signs, may have normal exam |
| Instability | Sudden onset after trauma or motion | Complete loss of function, arm held protectively | Visible deformity, positive apprehension, neurovascular deficit possible |
| Glenoid loosening | Progressive pain with activity, clicking | Gradual loss of ROM and strength | Crepitus, reduced ROM, mechanical symptoms |
| Nerve injury (axillary) | Variable - may be painless | Deltoid weakness, inability to abduct | Loss of deltoid contraction, lateral shoulder numbness |
| Periprosthetic fracture | Acute pain after fall or trauma | Sudden functional loss, unable to lift arm | Deformity, crepitus, ecchymosis, pain with movement |
Red Flags Requiring Urgent Assessment
Immediate evaluation needed: (1) Fever with wound drainage within 4 weeks = acute infection, (2) Sudden loss of function after trauma = instability or fracture, (3) Complete deltoid paralysis postop = axillary nerve injury requiring EMG, (4) Persistent pain with elevated CRP over 10 mg/L beyond 3 months = chronic infection, (5) Progressive mechanical symptoms = component loosening requiring imaging.
Investigations
First-Line Investigations
- Radiographs: AP, scapular Y, axillary lateral - assess component position, lucent lines, fracture
- Inflammatory markers: CRP, ESR - trending values more useful than absolute
- Complete blood count: WBC, differential - elevated in acute infection
- Comparison to previous: Serial radiographs essential for detecting progression
Advanced Imaging
- CT scan: Component version, bone defects, fracture characterization
- MRI: Rotator cuff integrity, soft tissue assessment (artifact from metal)
- Ultrasound: Aspiration guidance, fluid collection, subscapularis integrity
- Nuclear medicine: Tc-99 bone scan or WBC scan if infection suspected
Investigation Protocols
| Complication | Essential Tests | Advanced Tests | Diagnostic Threshold |
|---|---|---|---|
| Suspected infection | CRP, ESR, radiographs, joint aspiration | WBC scan, synovial markers (alpha-defensin), sonication | Synovial WBC greater than 3000 or 2 positive cultures |
| Instability | AP, scapular Y, axillary radiographs, neurovascular exam | CT scan for component version and position | Dislocation on imaging, component malposition on CT |
| Glenoid loosening | Serial radiographs (Lazarus zones), CRP to rule out infection | CT for bone defects, MRI for rotator cuff | Progressive radiolucent lines over 2mm, symptoms |
| Nerve injury | Clinical exam (deltoid, biceps strength), sensory testing | EMG/NCS at 3-4 weeks, follow-up at 3 months | Absent motor units on EMG, denervation potentials |
| Periprosthetic fracture | AP and lateral radiographs, component stability assessment | CT scan for fracture classification and surgical planning | Fracture visible on radiographs, classify by Vancouver |
Prosthesis Imaging
Management
General Management Principles
Management of shoulder arthroplasty complications follows key principles: (1) Exclude infection in any complication (aspiration if any doubt), (2) Assess component position with CT if instability or unexplained pain, (3) Document neurovascular status before and after any intervention, (4) Optimize patient factors (nutrition, diabetes control, smoking cessation), (5) Consider salvage options early (resection arthroplasty, fusion, amputation in severe cases).
Complication-Specific Management
| Complication | Conservative Options | Surgical Management | Salvage Options |
|---|---|---|---|
| Acute infection (less than 4 weeks) | None - surgical urgency | Debridement, polyethylene exchange, component retention if stable, 6+ weeks antibiotics | Two-stage revision, resection arthroplasty if failed |
| Chronic infection (over 4 weeks) | Suppressive antibiotics only if non-surgical candidate | Two-stage revision (remove, spacer, 6-12 weeks antibiotics, reimplant) | Permanent spacer, resection arthroplasty, fusion |
| Instability (first-time, well-positioned) | Closed reduction, immobilization 4-6 weeks, physical therapy | Open reduction, soft tissue repair, constrained liner if needed | Revision with position correction, larger glenosphere |
| Instability (recurrent or malpositioned) | None effective | Revision surgery: correct version/tilt, increase lateralization, constrained components | Fusion if multiple failed revisions |
| Glenoid loosening (asymptomatic) | Observation, activity modification, serial radiographs | None required | N/A |
| Glenoid loosening (symptomatic) | Activity modification, analgesics (temporary only) | Revision TSA (if cuff intact) or conversion to RSA (if cuff deficient), bone grafting 30-50% | Resection arthroplasty if poor bone stock |
| Nerve injury (neurapraxia) | Observation, physical therapy, brace for protection, reassurance (80-90% recover) | Exploration if no recovery by 6 months, neurolysis or grafting | Tendon transfers, functional bracing if permanent |
| Periprosthetic fracture Type B1 (stable component) | Conservative if non-displaced, or ORIF with plate/cables | ORIF preserving components | Revision if fixation fails |
| Periprosthetic fracture Type B2 (loose component) | None | Revision to long-stem prosthesis, bypass fracture by 2 cortical diameters | Structural allograft if severe bone loss (Type B3) |
Major Complications: Recognition and Management
1. Instability
Most Common RSA Complication
Instability occurs in 5-10% of RSA cases and 1-3% of anatomic TSA. In RSA, posterior instability accounts for 60% of cases and is often related to insufficient lateralization, excessive humeral retroversion, or subscapularis deficiency. Early recognition and assessment of component positioning is critical.
Instability Assessment and Management
Clinical: Sudden loss of function, pain, visible deformity, arm held in protective position.
Imaging: AP and axillary lateral radiographs confirm direction of dislocation.
Neurovascular: Document axillary nerve and radial pulse before and after reduction.
RSA posterior: Traction, adduction, gentle internal rotation.
TSA anterior: Traction, abduction, external rotation.
Post-reduction: Confirm concentricity on axillary view, assess stability arc of motion.
CT scan: Assess glenoid component version (target 10 degrees retroversion for RSA, 5 degrees for TSA).
Humeral version: Check humeral component retroversion (target 20-30 degrees).
Lateralization: Measure glenosphere offset in RSA (minimum 25mm from glenoid face).
First-time, well-positioned components: Trial of immobilization 4-6 weeks.
Recurrent or malpositioned: Revision surgery to correct component positioning.
Soft tissue deficiency: Consider constrained liner or augmented glenosphere.
Instability Risk Factors and Solutions
| Risk Factor | Mechanism | Prevention Strategy |
|---|---|---|
| Insufficient lateralization (less than 25mm) | Reduced deltoid tension, loss of stability arc | Use lateralized glenosphere or BIO-RSA design |
| Excessive humeral retroversion (over 30 degrees) | Posterior subluxation in neutral rotation | Target 20-30 degrees retroversion, check with CT |
| Subscapularis deficiency | Loss of anterior restraint, posterior instability | Repair subscapularis if possible, consider anterior augment |
| Superior glenoid tilt (over 10 degrees) | Inferior subluxation or anterior instability | Correct tilt with reaming or augmented baseplate |
2. Infection (Periprosthetic Joint Infection)
Microbiology
- Propionibacterium acnes: 30-40% of cases, indolent, male patients
- Staphylococcus epidermidis: 25-30%, biofilm former
- S. aureus: 15-20%, more acute presentation
- Culture-negative: 10-15%, consider P. acnes with extended culture
Diagnostic Criteria
- Major criteria: 2 positive cultures of same organism
- Minor criteria: Elevated ESR/CRP, positive histology, purulence
- Hold cultures: 14 days for P. acnes (slow growing)
- Sonication: Increases culture yield by 15-20%
Infection Management Algorithm
Acute (less than 4 weeks): Wound drainage, erythema, fever, elevated WBC.
Chronic (over 4 weeks): Persistent pain, elevated CRP (over 10 mg/L), mechanical symptoms.
Baseline labs: CBC, ESR, CRP before antibiotics if possible.
Aspiration: Under ultrasound or fluoroscopy, send for cell count, cultures, Gram stain.
Cell count: Greater than 3000 WBC with greater than 70% PMNs suggestive of infection.
Hold cultures: Request 14-day hold for P. acnes.
Debridement: Remove all infected tissue, obtain 5-6 tissue cultures.
Component retention: Only if acute (less than 4 weeks), stable components, known organism.
Polyethylene exchange: Remove and replace polyethylene liner if retaining components.
Sonication: Send removed components for sonication culture.
Initial empiric: Vancomycin plus ceftriaxone until cultures available.
P. acnes: Penicillin G 4 weeks IV, then amoxicillin 2-6 months oral.
S. aureus (MSSA): Cefazolin or nafcillin 6 weeks.
Biofilm coverage: Rifampin often added for Staph species.
Single-stage: Remove components, debride, reimplant same setting (controversial).
Two-stage: Remove components, antibiotic spacer, 6-12 weeks antibiotics, then reimplant.
Resection arthroplasty: If bone stock insufficient or patient not surgical candidate.
P. acnes: The Great Masquerader
Propionibacterium acnes causes indolent infections that can be easily missed. Symptoms may be limited to pain alone without systemic signs. Always hold cultures for 14 days and consider P. acnes in any male patient with persistent pain after shoulder arthroplasty, even with normal inflammatory markers.
3. Glenoid Component Loosening
Glenoid Loosening: Leading Cause of TSA Failure
Glenoid component loosening accounts for 30-40% of all TSA revisions. Radiolucent lines develop in 20-30% of patients by 10 years, but only 5-10% become symptomatic and require revision. The rocking horse phenomenon (eccentric loading with arm elevation) drives progressive loosening.
Lazarus Zones: Glenoid Radiolucent Line Assessment
| Zone | Location | Significance | Action |
|---|---|---|---|
| Zone 1 (Superior) | Superior quadrant of glenoid | High stress area, early indicator of loosening | Monitor closely if greater than 1mm width |
| Zones 2-3 (Anterior) | Anterior half of glenoid | Common with anterior eccentric wear | Consider revision if progressive and symptomatic |
| Zone 4 (Inferior) | Inferior quadrant | Associated with inferior tilt or subsidence | High concern if complete lucency around pegs |
| Zone 5 (Posterior) | Posterior half of glenoid | May indicate posterior glenoid wear | Assess glenoid version on CT |
| All zones (circumferential) | Complete lucency around component | Gross loosening, likely symptomatic | Revision surgery indicated |
Clinical Presentation
- Pain: Progressive, worse with activity and loading
- Mechanical symptoms: Clicking, clunking, catching sensation
- Reduced ROM: Especially forward elevation and rotation
- Weakness: Secondary to pain and mechanical block
Revision Planning
- CT scan: Assess bone defects (cavitary vs segmental)
- Rotator cuff: Check integrity - if torn, consider RSA
- Bone graft: Required in 30-50% of revisions for defects
- Component choice: Revision TSA vs conversion to RSA
4. Nerve Injuries
Nerve Injury Patterns in Shoulder Arthroplasty
| Nerve | Incidence | Mechanism | Recovery |
|---|---|---|---|
| Axillary nerve | 1-4% (highest risk) | Traction during exposure, retractor pressure, direct injury | 80-90% recover by 6 months |
| Musculocutaneous nerve | 0.5-1% | Traction, especially with excessive arm abduction | 85-95% recover by 6 months |
| Suprascapular nerve | 0.5-2% | Stretch during glenoid exposure, baseplate screw penetration | Variable - 60-80% recovery |
| Radial nerve | Less than 0.5% | Excessive arm extension or inferior retraction | Good recovery in over 90% |
| Brachial plexus | Less than 0.1% | Excessive traction, positioning injury, direct trauma | Poor recovery - permanent deficit common |
Nerve Injury Management Protocol
Document preop function: Essential for medicolegal protection and baseline.
Gentle retraction: Avoid excessive force on retractors near neurovascular structures.
Positioning: Avoid arm hyperextension or excessive abduction under anesthesia.
Axillary: Loss of deltoid contraction, numbness over lateral shoulder.
Musculocutaneous: Weak biceps, numbness lateral forearm.
Suprascapular: Weakness in external rotation (infraspinatus).
Observation: Most are neurapraxias recovering spontaneously.
Physical therapy: Maintain ROM, prevent contractures.
Patient education: Reassure about high recovery rate.
Baseline study: Establish severity and localization of injury.
Axonotmesis vs neurapraxia: Distinguish based on recruitment and amplitudes.
Follow-up EMG: At 3 months to assess for reinnervation.
Indications: Complete paralysis with no EMG recovery at 6 months.
Technique: Identify nerve, assess continuity, consider neurolysis or grafting.
Prognosis: Late exploration (over 6 months) has poor outcomes.
5. Periprosthetic Fractures
Vancouver Classification Adapted for Shoulder
Type A: Apophysis (greater/lesser tuberosity) - usually managed conservatively unless displaced over 5mm. Type B: Around or just below stem - most common, requires assessment of component stability (B1 stable, B2 loose, B3 poor bone stock). Type C: Well below stem - treat as native fracture, ORIF if displaced.
Risk Factors
- Patient: Osteoporosis, age over 70, rheumatoid arthritis
- Surgical: Excessive reaming, press-fit stems, cuff tear revision
- Component: Uncemented stems (3x risk vs cemented)
- Trauma: Falls, especially in RSA with altered biomechanics
Management Principles
- Type A: Sling immobilization unless over 5mm displacement
- Type B1: ORIF with cables/plates, preserve component
- Type B2: Revision to long-stem prosthesis
- Type B3: Structural allograft plus revision long-stem
- Type C: Standard fracture fixation techniques
Surgical Technique
Revision Surgical Techniques for Complications
General Principles of Revision Surgery
- Extended deltopectoral approach for adequate exposure
- Identify and protect neurovascular structures (axillary nerve often scarred)
- Careful subscapularis mobilization - may require extensive release
- Systematic component removal - humeral component first, then glenoid
Component Removal Techniques
Component Removal Strategies
| Component | Technique | Pitfalls to Avoid |
|---|---|---|
| Cemented humeral stem | Extended osteotomy or cement splitting osteotome | Spiral fracture, perforation, excessive bone loss |
| Press-fit humeral stem | Metal cutting instruments, flexible osteotomes | Proximal bone destruction, shaft perforation |
| Cemented glenoid | High-speed burr for cement, curettes for bone interface | Anterior perforation, excessive medial reaming |
| RSA baseplate | Remove screws first, peripheral release with osteotomes | Central screw damage to vault, fracture |
Bone Defect Management
- Cavitary defects: Impaction bone grafting with cancellous allograft
- Contained segmental (less than 25%): Cement filling or augments
- Large segmental (greater than 25%): Structural allograft or custom implants
- Glenoid vault deficiency: Consider metal augmented baseplate
Complications Specific to Implant Type
Reverse Shoulder Arthroplasty-Specific Issues
| Complication | Incidence | Mechanism | Management |
|---|---|---|---|
| Instability | 5-10% | Insufficient lateralization, malpositioning, tissue deficiency | Revision with corrected positioning or constrained liner |
| Scapular notching | 44-96% (radiographic) | Inferior glenosphere impingement on scapular neck | Usually asymptomatic - monitor for baseplate loosening |
| Baseplate failure | 2-4% | Poor bone stock, insufficient screws, notching | Revision with bone graft and larger baseplate |
| Acromial fracture | 1-4% | Deltoid overstretching, stress fracture from altered loading | Usually conservative - rest and immobilization |
| Hematoma | 3-5% | Increased dead space from lateralization | Drain use controversial - evacuate if symptomatic |
Scapular Notching: When to Worry
Scapular notching occurs when the inferior glenosphere impinges on the scapular neck during adduction. While common (up to 70% of cases), it is clinically significant in less than 10%. Worry when: notching progresses to Grade 3-4 (Nerot-Sirveaux), there is baseplate screw loosening, or patient develops pain and loss of adduction. Prevention: inferior glenosphere tilt, lateralization, or inferior eccentric glenosphere.
Understanding RSA-specific complications is essential given the increasing utilization of this prosthesis.
Prevention Strategies
Infection Prevention
- Preoperative: Optimize nutrition, control diabetes (HbA1c less than 7%), treat remote infections
- Antibiotic prophylaxis: Cefazolin 2g (3g if over 120kg) within 60 min of incision
- Skin preparation: Chlorhexidine alcohol superior to povidone-iodine
- P. acnes: Consider benzoyl peroxide wash protocol for male patients
- Drapes: Iodine-impregnated drapes may reduce infection
Instability Prevention
- Component positioning: Verify version and tilt intraoperatively with fluoroscopy
- Lateralization: Ensure minimum 25mm offset in RSA
- Soft tissue: Repair subscapularis anatomically in TSA
- Trial reduction: Test stability through arc before final components
- Avoid oversizing: Humeral component should not overstuff joint
Glenoid Loosening Prevention
- Bone preparation: Ream to cancellous bone, avoid anterior perforation
- Version correction: Correct excessive retroversion (target 5-10 degrees)
- Cement technique: Pressurize cement with finger or syringe
- Component choice: All-poly cemented pegged glenoid standard
- Patient selection: Consider RSA for young, high-demand patients
Nerve Injury Prevention
- Positioning: Avoid hyperextension, excessive abduction under anesthesia
- Retraction: Gentle retractor placement, avoid pressure on neurovascular structures
- Axillary nerve: Inferior capsular release under direct vision
- Suprascapular: Avoid superior baseplate screws over 30mm length
- Documentation: Record preoperative nerve function for baseline
The Power of Surgical Planning
Templating and preoperative planning reduce complications by 30-40%. Use CT-based 3D planning to: assess glenoid bone stock and version, plan correction strategy, determine implant size, and identify anatomic variants. In complex cases (revision, massive bone loss, dysplasia), patient-specific instrumentation or guides may be beneficial.
Revision Surgery: Principles and Outcomes
Revision Planning and Execution
CT scan: Essential for bone stock assessment, component position, version.
Infection workup: ESR, CRP, aspiration if any concern for infection.
Rotator cuff: MRI to assess integrity - determines RSA vs TSA revision.
Implant identification: Know the existing implant for extraction planning.
Glenoid: Preferential removal of cement, preserve bone stock.
Humeral: Flexible osteotomes, avoid perforation or fracture.
Bone defects: Assess size and location - cavitary vs segmental.
Cavitary defects: Impaction bone grafting with cancellous allograft.
Segmental defects (less than 25% surface): Augments or eccentric reaming.
Large segmental (over 25%): Structural allograft or custom components.
Glenoid: May use RSA baseplate for better fixation vs TSA re-glenoid.
Humeral: Long-stem component if bone loss or fracture risk.
Fixation: Cemented preferred in revision setting for immediate stability.
Slower protocol: 6 weeks immobilization common vs 2-4 weeks for primary.
ROM first: Passive ROM weeks 6-12, active ROM weeks 12-16.
Strengthening: Delayed until 4-6 months to allow bone/soft tissue healing.
Conversion from Failed TSA to RSA
Converting failed anatomic TSA to RSA is now the most common revision scenario. Indications: glenoid loosening with rotator cuff deficiency, subscapularis failure, or irreparable cuff tear. Challenges include glenoid bone loss (30-50% need grafting), humeral version mismatch (may need osteotomy), and deltoid scarring. Outcomes are 70-80% satisfactory vs 85-90% for primary RSA.
Postoperative Care
Postoperative Care Following Complication Management
Immediate Postoperative Period (0-6 weeks)
- Immobilization in sling - extended to 6 weeks for revision (vs 2-4 weeks primary)
- DVT prophylaxis: Mechanical and chemical (aspirin or LMWH)
- Pain management: Multimodal - regional block, paracetamol, NSAIDs, opioids PRN
- Wound monitoring: Daily inspection for drainage, erythema, dehiscence
Rehabilitation Protocol After Revision
Rehabilitation After Revision Shoulder Arthroplasty
| Phase | Timeframe | Goals | Precautions |
|---|---|---|---|
| Immobilization | 0-6 weeks | Protect repair, control pain, prevent stiffness | Sling at all times, no active motion |
| Passive ROM | 6-12 weeks | Restore passive motion | Therapist-assisted only, respect tissue healing |
| Active-assisted ROM | 12-16 weeks | Active motion, begin isometrics | No resisted exercises |
| Strengthening | 16-24 weeks | Progressive resistance, functional activities | Avoid heavy lifting greater than 5kg |
Specific Considerations
- Post-instability revision: May need prolonged immobilization (8 weeks) in position of stability
- Post-infection revision: Continue IV antibiotics per infectious disease guidance (typically 6-12 weeks)
- Post-fracture revision: Restrict activity until radiographic union confirmed
Outcomes
Outcomes After Complication Management
Revision Surgery Outcomes by Indication
Outcomes After Revision Shoulder Arthroplasty
| Indication | Satisfactory Rate | Re-revision Rate | Key Prognostic Factors |
|---|---|---|---|
| Instability | 70-80% | 10-15% at 5 years | Correct positioning, adequate soft tissue |
| Glenoid loosening | 75-85% | 8-12% at 5 years | Bone stock, cemented fixation |
| Infection (2-stage) | 80-85% | 5-10% at 5 years | Organism virulence, host factors |
| Periprosthetic fracture | 70-75% | 12-18% at 5 years | Bone quality, fracture pattern |
| Rotator cuff failure (TSA to RSA) | 80-85% | 8-12% at 5 years | Deltoid function, glenoid bone stock |
Functional Outcomes
- Active forward flexion: Average 100-120 degrees (vs 140-150 primary RSA)
- External rotation: Average 20-30 degrees
- Patient satisfaction: 70-80% (vs 85-90% primary)
- ASES score improvement: Average 30-40 points (less than primary)
Evidence Base and Key Trials
ASES Complications Database: Shoulder Arthroplasty Complications
- Multicenter registry: 2,588 shoulder arthroplasties (1,750 primary, 838 revision)
- Overall complication rate 10.3% for primary, 15.8% for revision
- Instability most common in RSA (5.3%), glenoid loosening most common in TSA (4.8%)
- Infection rate 2.1% for primary, 6.4% for revision
- Revision surgery within 2 years occurred in 4.1% of primary cases
Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR): Shoulder Arthroplasty
- From 2013-2022: 28,476 primary shoulder arthroplasties performed in Australia
- Cumulative revision rate at 10 years: 9.2% for TSA, 14.7% for RSA
- Leading causes of revision: instability (29%), infection (19%), loosening/lysis (17%)
- Revision for instability: 6.1% for RSA vs 1.8% for TSA at 5 years
- Uncemented glenoid components have 2.1x higher revision rate than cemented
Propionibacterium acnes in Shoulder Surgery: Strategies for Management
- P. acnes accounts for 30-40% of shoulder PJI, primarily in males
- Traditional 5-day culture misses 60% of P. acnes - requires 14-day culture
- Sonication of removed components increases culture yield by 15-25%
- Benzoyl peroxide wash protocol reduces P. acnes skin colonization by 70%
- Single-stage revision with long antibiotic course shows 85% success rate
Risk Factors for Instability After Reverse Shoulder Arthroplasty: Multicenter Study
- Multicenter retrospective: 2,452 RSA with 5.7% instability rate at 2 years
- Posterior instability 62%, anterior 28%, inferior 10%
- Risk factors: lateralization less than 25mm (OR 3.2), superior glenoid tilt over 10 degrees (OR 2.8)
- Subscapularis deficiency increased posterior instability risk (OR 2.1)
- Revision for instability required in 68% of cases - 79% successful
Glenoid Component Loosening in Total Shoulder Arthroplasty: 10-Year Outcomes
- Prospective cohort: 156 anatomic TSA with 10-year minimum follow-up
- Radiolucent lines in 28% at 10 years, but only 6.4% were symptomatic
- Progressive lucent lines (increasing width or extent) had 85% sensitivity for clinical loosening
- Cemented all-polyethylene pegged glenoid had lowest loosening rate (6.4% revision)
- Metal-backed glenoids had 4x higher revision rate (historical comparison)
Exam Viva Scenarios
Practice these scenarios to excel in your viva examination
Scenario 1: Acute Instability After RSA (approximately 3 minutes)
"A 72-year-old woman presents 6 weeks after reverse shoulder arthroplasty for rotator cuff arthropathy. She fell onto her operated shoulder yesterday and now has pain and inability to use her arm. X-rays show posterior dislocation of the RSA. How do you assess and manage this patient?"
Scenario 2: Persistent Pain After TSA - Infection Workup (approximately 4 minutes)
"A 58-year-old man presents with persistent shoulder pain 9 months after anatomic total shoulder arthroplasty for primary osteoarthritis. He describes constant aching pain that is worse at night and limits his function. He denies fever or wound issues. Inflammatory markers show CRP 18 mg/L (normal less than 5) and ESR 32 mm/hr (normal less than 20). Walk me through your diagnostic workup and management."
Scenario 3: Glenoid Loosening in Young TSA Patient (approximately 3 minutes)
"A 52-year-old active manual laborer presents 7 years after anatomic TSA for post-traumatic arthritis. He has progressive pain over 18 months, mechanical clicking, and reduced ROM. Radiographs show complete radiolucent lines around the glenoid component in all five Lazarus zones, with 5mm of superior tilt. CT shows cavitary bone loss posteriorly. How do you manage this case?"
MCQ Practice Points
Anatomy Question
Q: Which nerve is at highest risk during deltopectoral approach for shoulder arthroplasty?
A: Axillary nerve (1-4% injury rate). The axillary nerve exits the quadrilateral space and travels along the inferior capsule and undersurface of the deltoid. It is at risk during inferior capsular release, deltoid retraction, and placement of inferior retractors. Always document preoperative deltoid function and sensory examination over lateral shoulder for medicolegal protection. Most injuries are neurapraxias recovering within 3-6 months.
Classification Question
Q: What is the Lazarus classification system and why is it important?
A: The Lazarus classification describes radiolucent lines around glenoid components in five zones: superior (Zone 1), anterior (Zones 2-3), inferior (Zone 4), and posterior (Zone 5). Lines less than 1mm are often benign and stable; lines greater than 2mm or progressive lines indicate loosening. Complete lucency in all zones suggests gross loosening requiring revision. This system helps standardize radiographic assessment and predict need for revision surgery.
Treatment Question
Q: What is the optimal antibiotic regimen for Propionibacterium acnes shoulder PJI?
A: For P. acnes infection, the recommended regimen is penicillin G 18-24 million units/day IV for 4 weeks, followed by oral amoxicillin 2-6 months (total 6-12 weeks therapy). P. acnes is sensitive to penicillin in over 95% of cases. This indolent organism requires prolonged therapy due to biofilm formation. Cultures must be held 14 days as P. acnes is slow-growing and often missed with standard 5-day protocols.
Complication Question
Q: What is scapular notching in RSA and when is it clinically significant?
A: Scapular notching occurs when the inferior glenosphere impinges on the lateral scapular neck during adduction, causing bone erosion. It is very common (44-96% radiographically) but clinically significant in less than 10%. The Nerot-Sirveaux classification grades notching from Grade 1 (limited to pillar) to Grade 4 (extending to baseplate). Clinical significance occurs with Grade 3-4 notching causing pain, baseplate screw loosening, or loss of adduction. Prevention strategies include inferior glenosphere tilt, lateralization, and inferior eccentric glenosphere positioning.
Evidence Question
Q: What does the AOANJRR data show about shoulder arthroplasty revision rates?
A: The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) 2023 report shows cumulative 10-year revision rates of 9.2% for anatomic TSA and 14.7% for RSA, making shoulder arthroplasty the joint replacement with the highest revision rate. The leading causes of revision are instability (29%), infection (19%), and loosening/lysis (17%). RSA has higher instability revision rate (6.1% at 5 years vs 1.8% for TSA). Uncemented glenoid components have 2.1x higher revision rate than cemented components.
Management Question
Q: How do you manage a periprosthetic humeral shaft fracture (Vancouver Type B2) after shoulder arthroplasty?
A: Vancouver Type B2 indicates a fracture around or just below the stem with loose component. Management requires revision to a long-stem prosthesis (bypassing fracture by minimum 2 cortical diameters) with or without supplemental fixation (cables, cerclage wires, or plate). The fracture is typically addressed with cerclage cables proximally and a long-stem (150-200mm) cemented component for immediate stability. If bone quality is very poor (Type B3), structural allograft may be needed. Component retention (Type B1, stable component) can be managed with ORIF alone using cables and plate while preserving the stable prosthesis.
Australian Context and Medicolegal Considerations
AOANJRR Surveillance
- Mandatory reporting: All shoulder arthroplasties must be reported to AOANJRR
- 2013-2022 data: 28,476 primary procedures, 10-year revision rate 11.4% overall
- Implant performance: Registry tracks outcomes by implant design and fixation
- Outcome measures: Revision for any cause, revision for specific complications
- Use in practice: Registry data informs implant selection and patient counseling
Antibiotic Guidelines (ACSQHC)
- Prophylaxis: Cefazolin 2g (3g if over 120kg) within 60 minutes of incision
- Penicillin allergy: Vancomycin 15-20 mg/kg IV (over 60 minutes, start 90 min before incision)
- Duration: Single dose for clean cases, may extend to 24 hours for complex/revision
- P. acnes coverage: Consider adding clindamycin in male patients (off-label)
- Therapeutic Guidelines (eTG): Follow for PJI treatment protocols
Medicolegal Considerations in Shoulder Arthroplasty
Key documentation requirements to reduce litigation risk:
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Preoperative consent: Discuss specific complications (infection 2-6%, instability 1-10% depending on implant, nerve injury 1-4%, loosening requiring revision 10-15% by 10 years, need for future revision surgery). Document alternatives discussed (conservative management, arthroscopy, alternate implants).
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Surgical site marking: Mark correct side with patient awake, verify with timeout before incision.
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Implant tracking: Record implant type, size, lot numbers in medical record and registry. Keep implant stickers in patient chart.
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Nerve function: Document preoperative axillary, musculocutaneous, radial nerve function. Reassess immediately postop and at all follow-ups. If deficit develops, obtain EMG at 3-4 weeks and document management plan.
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Component positioning: Intraoperative fluoroscopy images showing component position. Consider postoperative CT for complex cases or instability.
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Infection prevention: Document prophylactic antibiotic timing, dose, and agent. Note skin preparation technique. Record implant handling protocols.
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Informed consent for revision: Higher complication rates (2-3x primary), lower functional outcomes (10-20 points on outcome scores), possibility of further revision surgery.
Common litigation issues: Nerve injury not documented preoperatively (difficult to prove timing), infection attributed to inadequate prophylaxis or poor technique, component malposition causing instability or loosening, failure to recognize and treat complications promptly, inadequate consent discussion of revision risk.
PBS Medications for PJI
- Cefazolin: PBS listed, first-line prophylaxis
- Vancomycin: PBS restricted - requires approval for prophylaxis
- Penicillin G: PBS listed for P. acnes treatment (benzylpenicillin)
- Amoxicillin: PBS listed for oral step-down therapy
- Rifampin: PBS listed, often used adjunctively for biofilm coverage
SHOULDER ARTHROPLASTY COMPLICATIONS
High-Yield Exam Summary
Major Complications by Frequency
- •Instability: 5-10% RSA (posterior 60%), 1-3% TSA (anterior from subscap failure)
- •Glenoid loosening: 20-30% radiolucent lines by 10 years, 5-10% symptomatic revision
- •Infection: 2-6% overall, P. acnes 30-40% (males, indolent), S. epi 25-30%
- •Nerve injury: Axillary 1-4% (most common), musculocutaneous 0.5-1%, 80-90% recover
Classification and Timing
- •Early (less than 3mo): Infection, nerve injury, instability, fracture
- •Intermediate (3mo-2yr): Periprosthetic fracture, component loosening
- •Late (over 2yr): Glenoid wear, osteolysis, subscapularis failure, cuff tear
- •Lazarus zones: Superior (1), anterior (2-3), inferior (4), posterior (5) - assess width and progression
Management Algorithms
- •Instability: CT to assess components, closed reduction if well-positioned, revise if malpositioned (insufficient lateralization less than 25mm, excessive retroversion over 30 degrees, superior tilt over 10 degrees)
- •Infection: Aspiration with 14-day culture for P. acnes, debridement if acute less than 4wks, two-stage revision if chronic or biofilm
- •Glenoid loosening: MRI for cuff integrity, revision TSA if cuff intact, convert to RSA if cuff deficient, bone graft in 30-50%
- •Nerve injury: Document preop, EMG at 3-4wks if no recovery, explore if no recovery by 6mo
Surgical Pearls
- •RSA instability prevention: Lateralization minimum 25mm, humeral retroversion 20-30 degrees, correct glenoid tilt (less than 10 degrees superior)
- •Infection prevention: Cefazolin 2g (3g if over 120kg) within 60min, chlorhexidine alcohol prep, benzoyl peroxide for males (P. acnes)
- •Glenoid loosening prevention: Cemented all-poly pegged glenoid, pressurize cement, correct version to 5-10 degrees retroversion
- •Nerve protection: Gentle retraction, avoid hyperextension positioning, inferior capsule release under vision
Key Evidence and Registry Data
- •AOANJRR 2023: 10-year revision rate 9.2% TSA, 14.7% RSA; instability 29%, infection 19%, loosening 17%
- •Uncemented glenoid: 2.1x higher revision rate vs cemented
- •P. acnes treatment: Penicillin G 4wks IV then amoxicillin 2-6mo oral, hold cultures 14 days
- •Revision outcomes: 60-70% good results vs 85-90% primary, 2-3x higher complication rate
Australian Context
- •AOANJRR mandatory reporting: All shoulder arthroplasties must be registered
- •PBS antibiotics: Cefazolin prophylaxis, penicillin G for P. acnes treatment
- •Medicolegal: Document preop nerve function, consent for revision risk 10-15% at 10yr, implant tracking with registry