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Total Hip Arthroplasty Bearing Surfaces

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Total Hip Arthroplasty Bearing Surfaces

Comprehensive guide to THA bearing surfaces - metal-on-polyethylene, ceramic-on-polyethylene, ceramic-on-ceramic, metal-on-metal, dual mobility, wear rates, particle disease, and AOANJRR data for orthopaedic exam

complete
Updated: 2024-12-17
High Yield Overview

THA BEARING SURFACES - MATERIALS SCIENCE IN PRACTICE

Wear Rates | Particle Disease | Material Properties | Patient Selection

0.1mm/yrHXLPE wear (10x less than conventional)
4-5µm/yrCeramic-on-ceramic wear (lowest)
MoPMost common globally (HXLPE standard)
0%MoM usage today (historical failure)

BEARING SURFACE OPTIONS

Metal-on-HXLPE
PatternMost common, low wear, proven
TreatmentStandard for most patients
Ceramic-on-HXLPE
PatternLower wear than MoP, no squeaking
TreatmentYoung active patients
Ceramic-on-Ceramic
PatternLowest wear, hard-on-hard
TreatmentYoung patients accepting squeak risk
Dual Mobility
PatternLarge effective head, low dislocation
TreatmentHigh instability risk patients

Critical Must-Knows

  • HXLPE (highly cross-linked polyethylene) has replaced conventional PE - 90% reduction in wear
  • Ceramic-on-ceramic has lowest wear but risk of squeaking (1-5%) and fracture (rare under 0.1%)
  • Metal-on-metal failed due to ALVAL (pseudotumor), metallosis, high revision rates - essentially abandoned
  • Dual mobility reduces dislocation by 50-75% - excellent for instability risk
  • Particle disease (osteolysis) driven by volume and biologic activity of wear debris

Examiner's Pearls

  • "
    HXLPE is standard - cross-linking reduces wear but decreases mechanical properties
  • "
    Large heads (36mm+) reduce dislocation but increase volumetric wear in MoP
  • "
    Ceramic has excellent wear but brittleness - avoid in high-impact activities
  • "
    MoM abandoned due to ALVAL - chromium and cobalt ion release causes pseudotumor

Critical THA Bearing Surface Exam Points

HXLPE is the Standard

Highly cross-linked polyethylene (HXLPE) has replaced conventional PE in over 90% of THAs. Irradiation cross-linking reduces wear by 90% but decreases fatigue strength. Not recommended for thinner liners (under 6mm). AOANJRR shows excellent survivorship.

Ceramic Benefits and Risks

Ceramic-on-ceramic has lowest wear (4-5 micrometers/year) but carries risk of squeaking (1-5%) and fracture (under 0.1%). Modern generation ceramics (alumina matrix composite, Biolox Delta) have lower fracture risk than older alumina.

MoM Historical Failure

Metal-on-metal failed catastrophically. Chromium/cobalt ion release causes ALVAL (aseptic lymphocytic vasculitis-associated lesion) with pseudotumor formation, soft tissue destruction. MHRA issued alerts 2010-2012. Essentially abandoned globally. Know surveillance protocols for legacy patients.

Particle Disease Mechanism

Osteolysis results from macrophage response to wear particles. Polyethylene particles (0.1-10 micrometers) are most osteolytic per particle, but volume matters. HXLPE dramatically reduced osteolysis rates. Size, number, and biologic activity all contribute.

Bearing Surface Selection by Patient Profile

Patient ProfileFirst ChoiceAlternativeAvoid
Standard patient (over 65, low demand)MoP (metal-on-HXLPE), 32-36mm headCeramic-on-HXLPE if young end of rangeMoM (obsolete)
Young active (under 50, high demand)Ceramic-on-ceramic or Ceramic-on-HXLPEMoP with large HXLPE head (36mm+)Conventional PE, thin liners
High dislocation risk (revision, neurologic, cognitive)Dual mobility (MoP or Ceramic-on-HXLPE)Large head MoP (36-40mm) with constraintSmall heads (under 32mm)
Obesity, high impact sportsMoP (HXLPE), ceramic-on-HXLPEReinforced ceramic-on-ceramic (Biolox Delta)Older generation ceramics, conventional PE
Metal allergy historyCeramic-on-ceramic or Ceramic-on-HXLPEOxidized zirconium-on-HXLPEMoP (standard cobalt-chrome), MoM
Mnemonic

HXLPE - Properties of Highly Cross-Linked Polyethylene

H
Highly cross-linked
Irradiation creates cross-links between polymer chains
X
eXcellent wear resistance
90% reduction in wear vs conventional PE
L
Lower fatigue strength
Trade-off - decreased mechanical properties
P
Polyethylene standard
Used in over 90% of modern THAs
E
Essential thickness (over 6mm)
Thinner liners risk fracture due to reduced strength

Memory Hook:HXLPE is the modern standard but remember the minimum thickness requirement

Mnemonic

CERAMIC - Ceramic Bearing Considerations

C
Cleanest articulation
Lowest wear rate (4-5 micrometers/year)
E
Excellent for young patients
Longevity advantage in high-demand patients
R
Risk of squeaking
1-5% incidence, multifactorial causes
A
Alumina matrix composite (Biolox Delta)
Modern generation - higher strength than pure alumina
M
Microseparation causes noise
Edge loading from component malposition
I
Impaction fracture risk
Brittle material - avoid high-impact activities
C
Cost is higher
Premium material with increased expense

Memory Hook:CERAMIC benefits and risks - lowest wear but squeaking and fracture potential

Mnemonic

ALVAL - Metal-on-Metal Failure Mechanism

A
Aseptic
Non-infectious inflammatory process
L
Lymphocytic
Delayed hypersensitivity type IV reaction
V
Vasculitis
Blood vessel inflammation
A
Associated
Linked to metal debris
L
Lesion (pseudotumor)
Soft tissue mass, can be destructive

Memory Hook:ALVAL is the devastating complication that ended MoM - know it for legacy patient surveillance

Mnemonic

WEAR - Factors Affecting Bearing Surface Wear

W
Weight of patient
Higher loads increase wear
E
Exercise level/activity
Gait cycles per year drive cumulative wear
A
Alignment and position
Edge loading dramatically increases wear
R
Roughness of surface
Scratches or third-body debris accelerate wear

Memory Hook:WEAR factors - remember it's not just the material but also mechanical environment

Overview and Historical Context

Bearing surface selection is one of the most important decisions in total hip arthroplasty, directly impacting longevity, wear, particle disease, and revision risk. The evolution of bearing surfaces reflects advances in materials science and hard-earned lessons from clinical failures.

Historical evolution:

  • 1960s-1990s: Charnley's metal-on-conventional polyethylene (MoP) established the gold standard
  • 1970s-1980s: First ceramic bearings introduced (alumina-on-alumina)
  • 1990s-2000s: Metal-on-metal (MoM) resurgence for large heads and young patients
  • 2000s: Introduction of highly cross-linked polyethylene (HXLPE)
  • 2010-2012: MoM catastrophic failure - MHRA alerts, widespread abandonment
  • 2010s-present: HXLPE becomes standard, ceramic refinements, dual mobility expansion

The Charnley Revolution

Sir John Charnley's low-friction arthroplasty using metal femoral head on polyethylene acetabular component with bone cement established THA as a reliable procedure. His principle of low friction (small 22mm head) minimized wear but increased dislocation risk - modern surgery balances these competing factors.

Current landscape (2024):

  • Metal-on-HXLPE: 70-80% of primary THAs globally (most common)
  • Ceramic-on-HXLPE: 10-15% (growing in young patients)
  • Ceramic-on-ceramic: 5-10% (selected young patients)
  • Dual mobility: 5-10% in primary THA, higher in revision (20-30%)
  • Metal-on-metal: Less than 1% (legacy cases, essentially abandoned)

Australian context (AOANJRR data): The AOANJRR provides world-leading registry data on bearing surface performance. Key findings inform Australian practice patterns and exam answers.

Anatomy and Biomechanics - Tribology Fundamentals

Tribology fundamentals:

Tribology is the science of friction, wear, and lubrication. In THA, the bearing surface operates under:

  • Loads: 2-8x body weight during gait
  • Cycles: 1-2 million cycles per year for active patient
  • Lubrication: Synovial fluid (boundary and fluid film lubrication)

Wear mechanisms:

  1. Adhesive wear: Material transfer between surfaces
  2. Abrasive wear: Hard particles (cement, bone, metal) scratch softer surface
  3. Fatigue wear: Cyclic loading causes subsurface crack propagation
  4. Corrosion: Electrochemical degradation (especially in MoM)

Stribeck Curve and Lubrication

The Stribeck curve describes lubrication regimes. THA operates in mixed lubrication (boundary + fluid film). Large heads with good clearance promote fluid film lubrication, reducing wear. This explains why proper component positioning and head size selection matter.

Material properties critical for bearings:

Material Properties Comparison

MaterialHardness (HV)Elastic Modulus (GPa)Fracture Toughness
Polyethylene (UHMWPE)Low (20-30)1High (ductile)
Cobalt-Chrome AlloyHigh (400-500)210Moderate
Alumina CeramicVery High (2000+)380Low (brittle)
Biolox Delta (AMC)Very High (2000+)358Moderate (improved)
Oxidized ZirconiumHigh (1300+)200Moderate

Head size effects:

  • Small heads (22-28mm): Low volumetric wear, high dislocation risk, limited ROM
  • Large heads (36-40mm+): Low dislocation risk, high ROM, increased volumetric wear in MoP
  • Optimal balance: 32-36mm for most patients with HXLPE

The relationship between head size and wear is complex - linear wear rate may increase slightly but dislocation risk decreases significantly.

Classification Systems - Bearing Surface Types

Conventional (non-cross-linked) polyethylene:

Historical standard (1960s-2000s):

  • Ultra-high molecular weight polyethylene (UHMWPE)
  • Gamma sterilization in air
  • Wear rate: 0.1-0.2mm per year (linear)
  • Volumetric wear increases with head size

Problems with conventional PE:

  • Particle disease: 0.1-10 micrometer particles highly osteolytic
  • Osteolysis: 10-40% at 10-15 years
  • Revision for wear: Leading cause of late THA failure
  • Oxidative degradation: Free radicals from sterilization cause aging

Current status:

  • Essentially obsolete in primary THA
  • May still be used in constrained liners (better mechanical properties)
  • Historical importance for understanding particle disease

Conventional PE taught us about particle disease but has been superseded by HXLPE.

Highly cross-linked polyethylene - modern standard:

Manufacturing process:

  1. Irradiation: Gamma or electron beam (50-100 kGy) - creates cross-links
  2. Post-irradiation treatment:
    • Remelting: Eliminates free radicals, lowest wear (most common)
    • Annealing: Below melting point, preserves mechanical properties better
    • Vitamin E stabilization: Newer method, combines benefits
  3. Result: Cross-linked polymer chains resist creep and wear

Benefits:

  • 90% reduction in wear vs conventional PE (0.01-0.05mm/year linear)
  • 95% reduction in osteolysis at 10+ year follow-up
  • Excellent longevity: Australian registry shows over 95% survivorship at 15 years
  • Allows larger head sizes (32-36mm) without excessive wear

Trade-offs:

  • Decreased mechanical properties: Lower ultimate strength, fatigue resistance
  • Minimum thickness requirement: 6-8mm to prevent fracture
  • Not suitable for thin liners: Small cups, obese patients with large heads may be problematic

HXLPE Thickness Rule

Minimum 6mm HXLPE thickness in any direction to prevent liner fracture. Smaller cups (size 48 or below) with large heads (38mm+) may violate this rule. Calculate: (cup inner diameter - head outer diameter) / 2 = liner thickness. This is a hard constraint.

Clinical outcomes (AOANJRR):

  • MoP (HXLPE) has lowest revision rate of common bearings in primary THA
  • 32-36mm heads optimal - balance wear and stability
  • No increase in liner fracture with modern HXLPE vs historical concerns

HXLPE represents one of the greatest advances in THA - it solved the particle disease problem.

Vitamin E stabilized polyethylene (newest generation):

Mechanism:

  • Alpha-tocopherol (Vitamin E) acts as antioxidant
  • Prevents oxidative degradation without remelting
  • Preserves mechanical properties while reducing wear

Potential advantages:

  • Better mechanical properties than remelted HXLPE
  • Maintained oxidation resistance
  • Theoretical improved crack resistance

Current evidence:

  • Excellent in vitro wear performance
  • Limited long-term clinical data (less than 10 years for most)
  • Australian registry does not yet distinguish Vitamin E vs standard HXLPE
  • Promising but needs more time to prove superiority

Clinical use:

  • Available from major manufacturers
  • Increasingly used in primary THA
  • May allow thinner liners safely (under investigation)

Vitamin E PE is the newest evolution but long-term data is still maturing.

Clinical Assessment - Patient Evaluation for Bearing Selection

Pre-operative assessment for bearing choice:

The selection of bearing surface is a critical decision that should be individualized based on comprehensive patient assessment. This is typically done during pre-operative consultation once THA is indicated.

Patient factors to assess:

Clinical Assessment for Bearing Selection

FactorAssessmentBearing Implications
AgeLongevity requirements, life expectancyUnder 50: ceramic options. Over 65: MoP standard
Activity levelSports, occupation, daily demandsHigh activity: ceramic-on-HXLPE or CoC. Standard: MoP
Dislocation riskPrior dislocation, abductor deficiency, neurologicHigh risk: dual mobility first choice
Metal allergy historyPrevious reactions, implant sensitivityAvoid MoP if severe. Choose ceramic-on-ceramic or CoP
BMIWeight optimization, liner thickness concernsObesity: ensure adequate liner thickness (over 6mm)
Patient preferencesAcceptance of squeak risk, cost considerationsDiscuss ceramic squeak risk. Balance expectations

History elements:

  • Age and life expectancy: Critical for longevity planning
  • Activity goals: What activities does patient want to return to?
  • Prior joint replacements: Experience with previous bearings
  • Allergy history: Metal sensitivity, implant reactions
  • Neuromuscular conditions: Parkinson's, stroke, dementia (dual mobility indication)
  • Falls risk: Cognitive impairment, balance disorders
  • Expectations: What has patient heard about different bearings?

Physical examination considerations:

  • BMI: Obesity affects liner thickness calculations
  • Hip pathology: Dysplasia, bone loss may affect cup size
  • Abductor function: Weakness indicates dual mobility consideration
  • Neuromuscular examination: Spasticity, tremor, weakness
  • Spinopelvic alignment: Fixed deformities affect stability (dual mobility)

Imaging assessment:

  • X-rays: Bone quality, acetabular anatomy, dysplasia
  • CT if complex anatomy: For accurate component sizing
  • Acetabular dimensions: Estimate cup size for liner thickness calculations

Bearing selection framework:

Step 1: Identify contraindications:

  • Metal allergy → Exclude MoP
  • High dislocation risk → Dual mobility
  • Very young (under 40) → Avoid conventional PE
  • MoM → Never use (obsolete)

Step 2: Assess longevity requirements:

  • Under 50 years → Ceramic options (CoC or CoP)
  • 50-65 years → Ceramic-on-HXLPE or MoP
  • Over 65 years → MoP standard (cost-effective)

Step 3: Discuss risks and benefits:

  • Ceramic: Squeak risk (1-5%), fracture risk (under 0.1%), best wear
  • HXLPE: Proven standard, no special risks, excellent outcomes
  • Dual mobility: IPD risk (under 1%), excellent stability

Step 4: Incorporate patient values:

  • Cost considerations (ceramic 2-3x more expensive)
  • Tolerance for squeak risk
  • Activity goals
  • Revision aversion (ceramic best longevity for young)

Shared Decision-Making

Bearing selection should be shared decision-making between surgeon and patient. Present options appropriate for the patient's profile, discuss risks/benefits, incorporate patient values. Document discussion and rationale in medical record. This is especially important for ceramic bearings (squeak risk) and dual mobility (IPD risk).

Pre-operative counseling:

  • HXLPE standard: "This is the proven standard bearing with excellent long-term results"
  • Ceramic options: "Lower wear for your young age, but 1-5% risk of squeaking which is usually benign"
  • Dual mobility: "Dramatically reduces your dislocation risk given your risk factors"
  • Activity modification: All bearings require avoiding high-impact sports

Documentation:

  • Bearing choice and rationale
  • Discussion of alternatives
  • Patient understanding and agreement
  • Special considerations (allergy, dislocation risk)

Clinical assessment for bearing selection is a systematic process balancing patient factors, surgeon experience, and evidence-based outcomes.

Ceramic Bearing Options - Hard-on-Hard Surfaces

Ceramic-on-ceramic (CoC) - hard-on-hard bearing:

Material evolution:

  • 1st generation (1970s): Pure alumina - high fracture risk (up to 1%)
  • 2nd generation (1990s): Improved alumina - fracture risk 0.2-0.5%
  • 3rd generation (2000s): High-purity alumina (Biolox Forte) - fracture under 0.1%
  • 4th generation (2010s+): Alumina matrix composite (Biolox Delta) - fracture under 0.01%

Biolox Delta (modern standard):

  • Alumina matrix with zirconia platelets for crack resistance
  • 20-25% higher strength than pure alumina
  • Maintains low wear characteristics

Advantages:

  • Lowest wear rate: 4-5 micrometers/year (10-20x less than HXLPE)
  • Minimal particle disease: Ceramic particles less biologically active
  • Hydrophilic surface: Better fluid film lubrication
  • Excellent longevity potential: Ideal for young patients (under 50)

Disadvantages:

  • Squeaking: 1-5% incidence (multifactorial)
  • Fracture risk: Under 0.1% with modern ceramics but catastrophic if occurs
  • Stripe wear: With component malposition or microseparation
  • Cost: 2-3x more expensive than MoP
  • Surgical technique demands: Impaction technique critical, no ceramic damage

Ceramic Fracture

Ceramic fracture is rare but devastating. Metal particles embedded in surrounding tissue make revision extremely difficult. All ceramic debris must be removed, usually requiring ceramic-on-HXLPE or MoP at revision. Prevention: avoid high-impact activities (rugby, martial arts), ensure perfect impaction technique.

Squeaking mechanism:

  • Stripe wear from edge loading (component malposition)
  • Microseparation during gait
  • Impingement causing lever-out
  • Patient factors: Thin patients, high activity
  • Most squeaking is benign - not associated with higher revision rates

Indications:

  • Young patients (under 50) with high longevity requirements
  • High activity level but not extreme impact sports
  • Patient accepts squeak risk after counseling

Contraindications:

  • High-impact sports (rugby, parachuting, martial arts)
  • Significant component malposition anticipated
  • Patient unwilling to accept squeak risk

CoC offers the best wear performance but demands perfect technique and patient selection.

Ceramic head on HXLPE liner (alternative hard-on-soft):

Rationale:

  • Combines ceramic head hardness with HXLPE wear resistance
  • Lower wear than metal-on-HXLPE
  • No squeaking risk (different mechanism than CoC)
  • Lower fracture concern (only head, not liner)

Wear performance:

  • 30-50% less wear than cobalt-chrome on HXLPE
  • Smoother ceramic surface reduces polyethylene shear stress
  • Scratch resistance prevents third-body wear

Advantages over CoC:

  • No squeaking
  • If ceramic head fracture (very rare), easier revision
  • Lower cost than CoC
  • More forgiving of minor malposition

Advantages over MoP:

  • Lower wear rate
  • Better for metal allergy concerns
  • Smoother surface finish

Current use:

  • Growing popularity especially in Europe and Asia
  • Excellent middle ground between MoP and CoC
  • Young patients who want ceramic benefits without squeak risk
  • Some surgeons use as routine bearing for all primary THAs

Ceramic-on-HXLPE Sweet Spot

Ceramic-on-HXLPE is arguably the optimal bearing for young patients - it provides better wear than MoP, no squeaking unlike CoC, and more forgiving than CoC. AOANJRR shows excellent outcomes. It may become the future standard as ceramic costs decrease.

AOANJRR data:

  • Ceramic-on-HXLPE shows lower revision rates than MoP in under 55 age group
  • Revision rate similar to CoC but without squeak revisions
  • Trend toward increased use in primary THA

Ceramic-on-HXLPE may represent the best balance of all bearing properties.

Oxidized zirconium (Oxinium) - ceramic surface on metal core:

Technology:

  • Zirconium alloy substrate heated to create 5-micrometer ceramic (zirconia) surface layer
  • Ceramic surface hardness with metal toughness underneath
  • Marketed as "best of both worlds"

Theoretical advantages:

  • Harder than cobalt-chrome, less scratching
  • Lower wear than metal-on-HXLPE
  • No fracture risk (metal core)
  • Lower metal ion release than cobalt-chrome

Clinical reality:

  • Wear reduction modest: 20-30% vs cobalt-chrome on HXLPE
  • Not as good as ceramic: Ceramic-on-HXLPE performs better
  • Limited registry data: Smaller numbers than other bearings
  • Niche indication: Metal allergy patients who don't want full ceramic

Current use:

  • Small market share (under 5%)
  • Some surgeons use routinely, most reserve for specific indications
  • Metal allergy without wanting full ceramic risk
  • Not clearly superior to ceramic-on-HXLPE

Oxinium represents an interesting technology but hasn't achieved widespread adoption.

Investigations - Bearing Performance Assessment

The rise and catastrophic fall of metal-on-metal:

Historical rationale (1990s-2000s):

  • Large head sizes possible (up to 60mm+) for stability
  • Low volumetric wear (self-polishing with use)
  • Young active patients with metal-on-metal resurfacing
  • Appeared to solve PE particle disease problem

Why MoM failed - the ALVAL disaster:

MoM Catastrophic Failure

Metal-on-metal is essentially abandoned due to devastating soft tissue reactions. This is one of the greatest failures in modern arthroplasty. Know this for exam - what went wrong, how to surveil legacy patients, and why it failed despite promising early wear data.

Failure mechanisms:

  1. Metal ion release: Chromium and cobalt ions from tribocorrosion and wear
  2. ALVAL (Aseptic Lymphocytic Vasculitis-Associated Lesion):
    • Type IV delayed hypersensitivity reaction
    • Lymphocytic infiltration, tissue necrosis
    • Pseudotumor formation (fluid-filled or solid mass)
  3. Soft tissue destruction: Muscles, tendons, nerves destroyed by pseudotumor
  4. Metallosis: Metal staining of tissues

Clinical presentation of MoM failure:

  • Pseudotumor on MRI or ultrasound
  • Pain disproportionate to radiographic findings
  • Elevated metal ions: Cobalt and chromium in blood
  • Soft tissue mass may be palpable
  • Implant may appear well-fixed on X-ray - soft tissue problem

MHRA (UK) and FDA alerts (2010-2012):

  • Medical Device Alert issued warning of high failure rates
  • Surveillance protocols mandated for all MoM patients
  • Many systems recalled or withdrawn from market
  • Class action lawsuits (DePuy ASR, Smith & Nephew BHR)

Surveillance of legacy MoM patients (essential to know):

MoM Surveillance Protocol (MHRA 2012)

TimingInvestigationsThreshold for Action
All MoM patients annuallyMetal ions (Co, Cr), clinical assessmentIons over 7 ppb (parts per billion)
Symptomatic or high ionsMRI MARS (metal artifact reduction sequence)Pseudotumor present, or growing
Large heads (over 36mm) or ASRMetal ions annually + MRI if symptomaticLower threshold for imaging
Revision thresholdSymptomatic + pseudotumor, or ions over 20 ppbRevision even if asymptomatic with large/growing tumor

Revision surgery for MoM failure:

  • Complete debridement of all necrotic tissue and metallosis
  • Ceramic or polyethylene liner (never metal again)
  • Large head removal - may need smaller head for adequate liner thickness
  • Soft tissue reconstruction may be needed (abductor repair common)
  • Outcomes poor if severe tissue destruction

Exam Question on MoM

Viva scenario: "A patient with MoM THA from 2008 presents with hip pain and cobalt ion level of 15 ppb. Management?" Answer: (1) This MoM bearing is at risk for ALVAL. (2) Order MRI MARS protocol to assess for pseudotumor. (3) If pseudotumor present, proceed to revision with complete debridement and bearing change. (4) If no tumor, close surveillance and consider revision if symptoms progress or ions increase. (5) Counsel re: failed technology.

Why MoM matters for exam:

  • Demonstrates importance of long-term surveillance and registry data
  • Example of biologic response mattering more than wear volume
  • Know ALVAL pathophysiology and surveillance protocols
  • Legacy patient management - many still have MoM implants

Current status:

  • Less than 1% of new THAs (essentially obsolete)
  • Used only in rare circumstances (metal allergy with ceramic unavailable)
  • Focus now on managing legacy patients with surveillance and revision

Metal-on-metal is a cautionary tale of technology adoption without adequate long-term data.

Dual Mobility Bearings

Dual mobility concept - articulation within articulation:

Design:

  • Small femoral head (22-28mm) articulates with polyethylene liner
  • Large outer diameter (typically 36-42mm+) articulates with metal shell
  • Two articulations: Small inner (primary), large outer (secondary)
  • Results in large effective head size for stability

Mechanism of dislocation resistance:

  1. Large head-to-neck ratio: Increased ROM before impingement
  2. Two centers of rotation: Impingement causes rotation, not dislocation
  3. Effective head diameter: 36-44mm equivalent for jump distance
  4. Retained ROM: Better than constrained liners

Indications for dual mobility:

  • High dislocation risk patients:
    • Revision THA (50-75% dislocation reduction)
    • Prior dislocation
    • Neuromuscular disorders (Parkinson's, stroke, dementia)
    • Abductor deficiency
    • Tumor resection
    • Spinal deformity or fusion
  • Primary THA in selected patients:
    • Elderly with cognitive impairment
    • High fall risk
    • Unable to comply with precautions

Dual Mobility Dislocation Reduction

Dual mobility reduces dislocation rates by 50-75% in high-risk patients. AOANJRR shows 1-2% dislocation rate with dual mobility vs 3-5% with standard bearings in revision THA. This is the primary indication - instability prevention, not treatment of all patients.

Bearing surface options in dual mobility:

  1. Standard: Cobalt-chrome head on HXLPE liner
  2. Ceramic-on-HXLPE: Ceramic head for lower wear
  3. All have metal shell outer bearing (shell-liner interface)

Concerns with dual mobility:

  1. Intraprosthetic dislocation (IPD):

    • Liner dissociates from head (rare, under 1%)
    • Usually from impingement or liner manufacturing issue
    • Requires open reduction (closed fails)
    • May need revision if recurrent
  2. Dual wear surfaces:

    • Inner bearing (head-liner): Low wear with HXLPE
    • Outer bearing (liner-shell): Concerns about wear
    • Total wear slightly higher than single bearing
    • Long-term data reassuring (over 20 years European experience)
  3. Metallosis from outer bearing:

    • Early designs had metal-on-metal outer bearing issues
    • Modern designs with retentive rim reduce motion at outer bearing
    • Most wear occurs at inner bearing

Australian registry data (AOANJRR):

  • Revision THA: Dual mobility significantly lower dislocation and revision rates
  • Primary THA: Growing use, excellent outcomes in high-risk patients
  • No increase in aseptic loosening or late complications
  • Trend toward increased adoption (currently 5-10% of primary, 20-30% revision)

Surgical technique considerations:

  • Avoid impingement (main cause of IPD)
  • Ensure snap-fit of liner into head (manufacturer-specific technique)
  • Component position standard targets (cup 40 degrees abduction, 15-20 anteversion)
  • Can't use constrained liner with dual mobility (different concept)

Future directions:

  • Some surgeons advocate routine use in all elderly patients
  • Ceramic-on-HXLPE dual mobility may further reduce wear
  • Improved outer bearing surfaces under development

Dual mobility is a major advance for instability prevention - know indications and IPD complication.

Wear Mechanisms and Particle Disease

Wear debris generation:

Particle size and biologic response:

Particle Size and Biological Activity

Particle TypeSize RangeBiological ResponseClinical Effect
Polyethylene0.1-10 micrometersHighly osteolytic per particleOsteolysis (main concern with conventional PE)
CeramicUnder 0.1 micrometers (nanometer)Low biological activityMinimal osteolysis
Metal (MoM)20-100 nanometersALVAL/hypersensitivity (ions)Pseudotumor, tissue destruction
PMMA cement1-100 micrometersModerate inflammatoryInterface osteolysis

The osteolysis cascade:

  1. Wear particles enter periprosthetic tissue through joint capsule, screw holes, thin implant-bone interface
  2. Macrophage activation: Particles phagocytosed by macrophages
  3. Cytokine release: TNF-alpha, IL-1, IL-6, RANKL
  4. Osteoclast activation: RANK-RANKL pathway
  5. Bone resorption: Progressive osteolysis
  6. Implant loosening: Loss of fixation from bone loss

Effective Joint Space Concept

The effective joint space is the path particles can travel - joint capsule, screw holes, thin bone-implant interface. Particles accumulate at weak points (stress risers, thin cement mantle, uncemented ingrowth surfaces). Granuloma formation causes progressive osteolysis and eventual loosening.

Factors determining osteolysis risk:

  1. Particle volume: Total amount of wear debris (HXLPE dramatically reduces this)
  2. Particle size: 0.1-10 micrometers most osteolytic
  3. Particle shape: Elongated worse than round
  4. Patient biology: Some patients more susceptible (genetic factors)
  5. Time: Cumulative exposure (why young patients at highest risk historically)
  6. Implant design: Access of particles to bone

HXLPE impact on osteolysis:

  • 95% reduction in osteolysis at 10-year follow-up vs conventional PE
  • Osteolysis rates now under 5% at 15 years (vs 30-40% historical)
  • Transformed THA outcomes in young patients
  • Most osteolysis now from other sources: cement, metal debris, backside wear

Backside wear (liner-shell interface):

  • Occurs when liner micromotion against metal shell
  • Locking mechanism critical
  • Diagnosis: Increasing metallosis without obvious bearing wear
  • Prevention: Adequate liner locking, avoid thin liners (under 3-4mm backside thickness)

Third-body wear:

  • Cement particles, bone chips, metal debris from components
  • Scratch polyethylene surface
  • Accelerate wear dramatically
  • Prevention: Meticulous surgical technique, thorough lavage, avoid cement extrusion

Management Algorithm

📊 Management Algorithm
tha bearing surfaces management algorithm
Click to expand
Management algorithm for tha bearing surfacesCredit: OrthoVellum

Standard patient (over 65, average activity):

First choice: Metal-on-HXLPE (32-36mm head)

Rationale:

  • Most proven long-term data (HXLPE over 15 years)
  • Lowest revision rates in registry data
  • Excellent wear performance (0.01-0.05mm/year)
  • Cost-effective
  • Forgiving of minor malposition

Head size selection:

  • 32mm: Good balance, most common
  • 36mm: Slightly more stability, acceptable wear with HXLPE
  • Avoid under 28mm (dislocation risk) or over 40mm (potential wear concerns)

Alternative: Ceramic-on-HXLPE

  • If patient younger end of range (65-70)
  • If long life expectancy
  • Slightly better wear than MoP
  • No squeak risk vs CoC

Avoid:

  • Conventional PE (obsolete)
  • MoM (failed technology)
  • CoC (unnecessary in this age group)
  • Dual mobility (unless instability risk factors)

For most patients over 65, MoP (HXLPE) with 32-36mm head is the gold standard.

Young patient (under 50, high activity):

First choice: Ceramic-on-Ceramic OR Ceramic-on-HXLPE

Ceramic-on-Ceramic:

  • Lowest wear rate (4-5 micrometers/year)
  • Best longevity potential (critical for 40-year implant life needed)
  • Modern ceramics (Biolox Delta) very low fracture risk
  • Accept squeak risk (counsel patient - 1-5% chance)

Ceramic-on-HXLPE:

  • No squeak risk (major advantage)
  • Lower wear than MoP (30-50% reduction)
  • More forgiving than CoC
  • Growing evidence base
  • Many surgeons' preference for young patients

Alternative: Large head MoP (36-40mm HXLPE)

  • If ceramic unavailable or cost prohibitive
  • Ensure adequate liner thickness (minimum 6mm)
  • Counsel about higher wear vs ceramic options
  • Still acceptable with modern HXLPE

Avoid:

  • Small heads (under 32mm) - dislocation risk over long life
  • MoM - failed technology especially in young patients
  • Conventional PE - will definitely fail

Young Patient Counseling

For patients under 50, discuss longevity requirements. A 40-year-old needs implant to last 40+ years. Ceramic options provide best wear performance. Counsel about squeak with CoC vs wear advantage. Ceramic-on-HXLPE may be optimal balance. Cost is secondary to longevity in this age group.

The key for young patients is minimizing wear to prevent particle disease over decades of use.

High dislocation risk patient:

First choice: Dual Mobility

Specific indications:

  • Revision THA (especially for instability)
  • Prior dislocation
  • Abductor deficiency (prior surgery, tumor, insufficiency)
  • Neuromuscular disorders: Parkinson's, CVA, dementia
  • Cognitive impairment (unable to follow precautions)
  • Spinal deformity or fusion (altered biomechanics)
  • Tumor resection (bone/soft tissue loss)

Dual mobility specifications:

  • Standard: CoCr head on HXLPE liner (most common)
  • Premium: Ceramic head on HXLPE liner (lower wear)
  • Head size: 22-28mm inner, 36-42mm+ effective outer
  • Ensure snap-fit of liner to head

Alternative: Large head (36-40mm) with constraint

  • If dual mobility unavailable
  • Constrained liner adds posterior lip but reduces ROM
  • Higher dislocation rate than dual mobility
  • Increased liner wear and fracture risk with constraint

Surgical technique emphasis:

  • Component position critical (avoid impingement → IPD)
  • Soft tissue repair (capsule, abductors)
  • Approach selection (posterior with repair vs anterior)

Counsel about:

  • 50-75% dislocation reduction with dual mobility
  • IPD risk (under 1%, requires open reduction)
  • Not a substitute for proper technique and positioning

Dual mobility has transformed outcomes in high-risk patients - know the indications.

Metal allergy or sensitivity:

Choice: Ceramic-on-Ceramic or Ceramic-on-HXLPE

  • Avoid all metal bearing surfaces
  • Ceramic head eliminates metal contact
  • Consider skin patch testing if history unclear
  • Titanium shells available (less allergenic than CoCr)

Obesity:

Challenge: High loads, thick soft tissues

  • Prefer HXLPE (standard or Vitamin E) - proven in high loads
  • Adequate liner thickness essential (calculate carefully)
  • May need smaller head to maintain liner thickness
  • Ceramic-on-HXLPE option if want best wear
  • Avoid CoC if BMI over 40 (higher fracture concern with impact)

Revision THA:

Choice depends on reason for revision:

  • Instability: Dual mobility (first choice)
  • Wear/osteolysis: HXLPE (ceramic head option for young)
  • Infection: Depends on bone loss, stability concerns
  • After MoM failure: HXLPE or ceramic-on-HXLPE, never metal again

Bone loss/dysplasia:

  • Dual mobility common due to instability risk
  • Larger cups (dysplasia) may limit liner options
  • Augments/structural graft may affect bearing choice

Cost constraints:

  • HXLPE standard bearing is cost-effective and excellent
  • Ceramic premium pricing may be prohibitive in some systems
  • Prioritize longevity in young patients despite cost
  • Dual mobility cost-effective if prevents revision for dislocation

Every patient requires individualized bearing selection based on multiple factors.

Surgical Technique - Bearing-Specific Considerations

Bearing-specific surgical pearls:

Metal-on-HXLPE surgical considerations:

Liner selection:

  • Calculate minimum liner thickness: (cup ID - head OD) / 2 = must be over 6mm
  • Example: 54mm cup, 36mm head = (54-36)/2 = 9mm thickness (safe)
  • Example: 48mm cup, 36mm head = (48-36)/2 = 6mm thickness (marginal)
  • Choose smaller head or larger cup if thickness under 6mm

Liner insertion:

  • Ensure complete seating (listen for snap/feel for stable rim lock)
  • Check locking mechanism integrity
  • Avoid backside damage (scratches accelerate backside wear)
  • Some systems require specific impaction technique

Head impaction:

  • Clean Morse taper thoroughly (no blood, debris)
  • Align head with taper, single firm strike
  • Avoid repeated impaction (damages taper)
  • Test stability before closure

Intraoperative issues:

  • Liner won't seat: Check for debris, shell deformation
  • Head won't lock: Check taper damage, blood contamination
  • Backside scratches: Consider liner replacement if severe

Standard HXLPE technique is straightforward and forgiving.

Ceramic bearing surgical technique (critical precision required):

Pre-operative planning:

  • Have backup plan (ceramic heads/liners can fracture during insertion)
  • Have alternative bearing available (MoP components)
  • Review manufacturer guidelines (technique varies by system)

Ceramic liner insertion:

  • Inspect liner carefully for cracks, chips (any damage = discard)
  • Use manufacturer-specific impactor
  • Single, firm, centered strike (multiple strikes risk fracture)
  • Never hit edge of liner (fracture risk)
  • Listen for solid seating sound

Ceramic head impaction:

  • Inspect head for damage (discard if any chips)
  • Clean taper meticulously (debris causes point loading = fracture)
  • Dry taper before head insertion
  • Align carefully, single centered strike
  • Never strike lateral edge of head
  • Avoid excessive force

Critical warnings:

  • Do not impinge ceramic on ceramic during trial reduction
  • No metal instruments touching ceramic articulating surfaces
  • Protect from impact during surgery
  • If ceramic cracks during insertion: remove all debris, convert to MoP

Trial reduction:

  • Use trial components (not actual ceramic)
  • Never reduce actual ceramic liner + head before final implantation
  • Assess stability with trials first

Ceramic technique demands perfect execution - any error risks fracture.

Dual mobility insertion technique:

Cup preparation:

  • Standard acetabular preparation
  • No specific concerns for dual mobility vs standard cup
  • Ensure adequate seating for locking mechanism

Liner placement:

  • Insert liner into cup first (manufacturer-specific)
  • Ensure complete snap-fit (critical to prevent IPD)
  • Test locking by attempting to remove liner (should resist)
  • Some systems have visual/tactile indicators

Head-liner assembly:

  • Critical step: Engage small femoral head into polyethylene liner
  • Requires specific technique (varies by manufacturer):
    • Some: Compress liner, insert head, release (snap-fit)
    • Some: Direct impaction
  • Verify complete engagement (feel/hear snap, inspect rim)
  • Head must be fully captured (any exposure risks dissociation)

Reduction:

  • Reduce large outer bearing into metal shell
  • Should reduce smoothly (if resistance, check for head-liner dissociation)
  • Check stability through full ROM

Intraoperative IPD:

  • If head separates from liner during trial or closure:
    • Stop immediately
    • Assess for impingement (component position, bone, osteophytes)
    • Re-assemble liner-head complex
    • Correct impingement source
  • Do not accept IPD as acceptable - requires correction

Position assessment:

  • Dual mobility does not compensate for malposition
  • Standard targets: 40 degrees abduction, 15-20 anteversion
  • Avoid impingement (primary cause of IPD)

Dual mobility technique focuses on ensuring complete liner-head engagement.

Complications Specific to Bearing Surfaces

Bearing-Specific Complications

BearingSpecific ComplicationIncidenceManagement
Conventional PEOsteolysis/particle disease30-40% at 15 yearsRevision with HXLPE, bone grafting
HXLPELiner fracture (thin liners)Under 1% if adequate thicknessRevision, ensure minimum 6mm
Ceramic-on-CeramicSqueaking1-5%Usually benign, revision if severe/painful
Ceramic-on-CeramicFracture (modern)Under 0.1%Revision, all debris removal, MoP or CoP
Ceramic-on-CeramicStripe wear1-3% with malpositionMay progress to fracture, revise if progressive
Metal-on-MetalALVAL/pseudotumor10-30% at 10 yearsRevision with debridement, bearing change
Dual MobilityIntraprosthetic dislocationUnder 1%Open reduction, may need revision
All bearingsDislocation1-5% (lower with DM/large heads)Closed reduction, address instability

HXLPE liner fracture:

  • Risk factors: Thin liners (under 6mm), large heads, obese patients, trauma
  • Presentation: Acute pain, instability, metallosis from exposed shell
  • Prevention: Calculate liner thickness, minimum 6mm rule
  • Treatment: Revision, ensure adequate thickness (may need smaller head)

Ceramic squeaking:

  • Mechanism: Microseparation, stripe wear, edge loading from malposition
  • Risk factors: Thin patients, high activity, component malposition, smaller cups
  • Presentation: Audible squeak with specific movements (sitting to standing, stairs)
  • Natural history: Most remain stable, not associated with higher revision
  • Management: Reassurance if benign, revision only if painful or patient distress severe

Ceramic fracture (modern ceramics):

  • Incidence: Under 0.1% with Biolox Delta
  • Causes: Impaction technique error, severe trauma, pre-existing damage
  • Presentation: Acute pain, grinding sensation, metallosis (embedded particles)
  • Treatment: Urgent revision, complete debridement (metal particles), convert to MoP or CoP
  • Prevention: Careful impaction, avoid ceramic damage, patient counseling on activity

ALVAL/Pseudotumor (MoM legacy):

  • Pathophysiology: Type IV hypersensitivity to metal ions, tissue destruction
  • Presentation: Pain, soft tissue mass, elevated metal ions, abnormal MRI
  • Diagnosis: MRI MARS protocol, metal ion levels (Co, Cr)
  • Grading: Pseudotumor size and tissue involvement
  • Treatment: Revision with complete debridement, bearing change (ceramic or PE), soft tissue reconstruction
  • Outcomes: Poor if severe tissue destruction, abductor deficiency common

Intraprosthetic dislocation (dual mobility):

  • Mechanism: Liner disengages from femoral head (not traditional dislocation)
  • Causes: Impingement, liner design/manufacturing, inadequate snap-fit
  • Presentation: Dislocation that cannot be closed reduced (key feature)
  • Diagnosis: X-ray shows liner outside head
  • Treatment: Open reduction required, assess for impingement, may need revision
  • Prevention: Avoid impingement, ensure proper liner seating intraoperatively

Postoperative Care and Surveillance

Standard bearing surveillance:

Immediate Postoperative (0-6 weeks)
  • Standard THA rehabilitation protocol (bearing-independent)
  • No bearing-specific restrictions for HXLPE or ceramic
  • Dual mobility: Standard precautions (not more restrictive)
  • Ceramic: Avoid direct trauma to hip (warn about falls)
Early Follow-up (6 weeks - 3 months)
  • Clinical assessment, X-rays
  • All bearings: Assess position, stability, early complications
  • Ceramic: Listen for squeaking (if present, document and counsel)
  • Dual mobility: Assess for early IPD (rare)
Annual Follow-up (Years 1-5)
  • Clinical and radiographic assessment
  • Standard bearings (MoP, CoC, CoP): Routine surveillance
  • MoM legacy patients: Metal ions annually, MRI if symptomatic or high ions
  • Ceramic: Document squeaking if present, assess if changing
Long-term Surveillance (5+ years)
  • Every 1-2 years clinical/radiographic
  • HXLPE: Monitor for late osteolysis (rare but possible)
  • Ceramic: Long-term squeak assessment, wear evaluation
  • MoM: Lifetime surveillance required (metal ions, MRI if indicated)
  • All: Monitor for aseptic loosening, infection, periprosthetic fracture

MoM-specific surveillance (MHRA 2012 guidelines):

MoM Surveillance Protocol

All patients with metal-on-metal bearings require lifetime surveillance. This includes hip resurfacing and large head (over 36mm) MoM THAs. Follow MHRA 2012 guidance or equivalent local protocol. Failure to surveil is medicolegal risk.

MHRA protocol summary:

  1. Annual clinical assessment - pain, function, soft tissue mass
  2. Annual metal ion levels - cobalt and chromium
  3. MRI if:
    • Symptomatic (pain, mass)
    • Metal ions over 7 ppb
    • ASR or other recalled system
    • Large head (over 36mm)
  4. Revision if:
    • Symptomatic with pseudotumor
    • Asymptomatic but large/growing pseudotumor
    • Metal ions persistently over 20 ppb

Activity restrictions by bearing:

Activity Recommendations

BearingRecommended ActivitiesCaution ActivitiesAvoid Activities
HXLPE (MoP)Walking, cycling, golf, swimmingJogging, doubles tennisImpact sports, marathon running
Ceramic-on-HXLPEWalking, cycling, golf, swimming, joggingSingles tennis, skiingContact sports, high-impact
Ceramic-on-CeramicWalking, cycling, golf, swimmingJogging, skiing, tennisRugby, martial arts, parachuting, extreme impact
Dual MobilityAll standard activitiesHigh-impact sportsExtreme ROM sports (yoga, gymnastics may risk IPD)

Patient education key points:

  • HXLPE: Proven standard, excellent longevity, no special restrictions
  • Ceramic: Avoid high trauma risk, report squeaking (usually benign)
  • Dual mobility: Excellent stability, rare IPD risk
  • MoM legacy: Lifetime surveillance required, report any symptoms immediately

Long-term outcomes monitoring:

  • Registry data (AOANJRR in Australia) provides population-level outcomes
  • Individual patient: Clinical symptoms most important
  • Radiographic loosening: Progressive radiolucent lines, migration
  • Osteolysis: Expansile lucencies, cortical thinning

Outcomes and Prognosis - Long-term Performance

Long-term outcomes by bearing surface:

Metal-on-HXLPE (most data):

  • 15-year survivorship: 94-96% (AOANJRR data)
  • Wear rate: 0.01-0.05mm/year linear
  • Osteolysis: Under 5% at 15 years (vs 30-40% conventional PE)
  • Excellent outcomes across all age groups
  • Most predictable long-term performance

Ceramic-on-HXLPE (emerging data):

  • 15-year survivorship: 95-96% (highest of common bearings)
  • Wear rate: 30-50% less than metal-on-HXLPE
  • Best outcomes in under 55 age group (AOANJRR)
  • Growing body of 10-15 year data
  • May become future standard

Ceramic-on-Ceramic:

  • 15-year survivorship: 92-95%
  • Lowest wear rate: 4-5 micrometers/year
  • Squeak: 1-5%, most benign (not associated with higher revision)
  • Fracture: Under 0.1% with modern ceramics (Biolox Delta)
  • Young patients: Best wear performance over decades
  • Revision for squeak: Under 1% (rare indication)

Dual Mobility:

  • Dislocation reduction: 50-75% vs conventional bearings
  • Revision THA: 1-2% dislocation rate (vs 5-15% standard)
  • Primary THA high-risk: 1-3% dislocation rate
  • IPD rate: Under 1%
  • No increase in loosening vs standard bearings
  • Excellent outcomes in appropriate indications

Metal-on-Metal (historical - for comparison):

  • 10-15 year revision rate: 15-30% (catastrophic failure)
  • ALVAL/pseudotumor: 10-30% at 10 years
  • Essentially abandoned globally
  • Legacy patients require ongoing surveillance

Prognostic factors for bearing longevity:

Factors Affecting Bearing Outcomes

FactorImpact on OutcomesOptimization Strategy
Patient ageYoung patients higher wear (more cycles)Use lowest-wear bearing (ceramic options)
Activity levelHigh activity increases wearCounsel activity modification, choose durable bearing
Component positionMalposition accelerates wear, increases complication riskPrecision positioning, avoid outliers
Head sizeLarger heads: more stability, more volumetric wearBalance at 32-36mm for most patients
BMIObesity increases loads and wearWeight optimization pre-operatively
Bearing qualityHXLPE dramatically better than conventional PEUse modern bearings (HXLPE standard)

Age-specific outcomes (AOANJRR data):

Under 55 years:

  • Ceramic-on-HXLPE: Lowest revision rate (4-5% at 15 years)
  • Metal-on-HXLPE: Acceptable (5-7% at 15 years)
  • Longevity critical (may need 40+ year implant life)
  • Recommendation: Ceramic options when possible

55-65 years:

  • Ceramic-on-HXLPE and Metal-on-HXLPE: Similar excellent outcomes
  • Individual factors guide choice (activity, preference, cost)
  • Both excellent options

Over 65 years:

  • Metal-on-HXLPE: Standard of care, excellent outcomes
  • Cost-effective
  • Longevity less critical (20-25 year life expectancy)
  • Ceramic options reasonable but not necessary for most

Patient satisfaction:

  • Overall satisfaction: Over 90% with modern bearings
  • Squeak impact: Variable - some patients unbothered, others distressed
  • Function: Excellent with all modern bearings
  • Pain relief: 90-95% significant improvement
  • Return to activities: Most patients achieve desired activity level

Bearing-specific patient-reported outcomes:

  • HXLPE: High satisfaction, no bearing-specific concerns
  • Ceramic: High satisfaction if no squeak, decreased if squeak present
  • Dual mobility: Excellent satisfaction, confidence in stability
  • MoM: Low satisfaction due to surveillance burden and complications

Registry data confirms:

  • HXLPE revolution transformed THA outcomes
  • Ceramic options further improve outcomes in young patients
  • Dual mobility solves instability problem
  • Modern bearings achieve 95%+ survivorship at 15 years

These excellent outcomes are why THA is considered one of the most successful surgical procedures in medicine.

Evidence Base

Level II
📚 Highly Cross-Linked Polyethylene in THA - Long-term Follow-up
Key Findings:
  • 20-year follow-up of HXLPE vs conventional PE. HXLPE showed 95% reduction in osteolysis (3% vs 30%) and 90% reduction in linear wear rate. No increase in liner fracture. HXLPE revolutionized THA longevity.
Clinical Implication: HXLPE is the modern standard for polyethylene bearings - dramatically reduced particle disease. Conventional PE is obsolete.
Source: Oral et al. J Bone Joint Surg Am 2020

Level III
📚 Ceramic-on-Ceramic THA - Meta-Analysis of Outcomes
Key Findings:
  • Meta-analysis of 38 studies, 9,293 hips. Ceramic-on-ceramic had lowest wear rate, reduced osteolysis vs MoP. Squeaking incidence 1-5%. Modern ceramics (Biolox Delta) had fracture risk under 0.1%. Best longevity potential for young patients.
Clinical Implication: Ceramic-on-ceramic offers best wear performance but requires patient counseling about squeaking. Modern ceramics much safer than historical.
Source: Hu et al. J Arthroplasty 2015

Level II
📚 Metal-on-Metal Failure - ALVAL and Pseudotumor
Key Findings:
  • Large head MoM showed 10-15% failure at 5 years from ALVAL/pseudotumor. Cobalt/chromium ions cause hypersensitivity reaction with soft tissue destruction. Elevated ions (over 7 ppb) predict failure. MoM surveillance mandatory.
Clinical Implication: MoM bearing failed catastrophically. Know surveillance protocol (MHRA 2012) for legacy patients. Metal ions and MRI required annually. Revise if symptomatic or elevated ions.
Source: Langton et al. J Bone Joint Surg Br 2010

Level III
📚 Dual Mobility in Revision THA - Systematic Review
Key Findings:
  • Systematic review of dual mobility in revision THA. Dislocation rate 1-2% vs 5-15% with conventional bearings. 50-75% dislocation risk reduction. Intraprosthetic dislocation rate under 1%. Excellent solution for instability.
Clinical Implication: Dual mobility dramatically reduces dislocation in high-risk patients. First choice for revision THA and primary THA with instability risk factors.
Source: Darrith et al. J Arthroplasty 2018

Level I
📚 AOANJRR 2023 Annual Report - Bearing Surface Outcomes
Key Findings:
  • Analysis of over 500,000 primary THAs. Ceramic-on-HXLPE had lowest revision rate (4-5% at 15 years), especially in under 55 age group. Metal-on-HXLPE excellent in all ages (5-6% at 15 years). MoM highest revision (15-30%). 32-36mm heads optimal.
Clinical Implication: Registry data confirms ceramic-on-HXLPE and metal-on-HXLPE as optimal bearings. Head size 32-36mm is sweet spot. Reference AOANJRR in Australian exam answers.
Source: Australian Orthopaedic Association National Joint Replacement Registry 2023

Exam Viva Scenarios

Practice these scenarios to excel in your viva examination

VIVA SCENARIOStandard

Scenario 1: Bearing Selection for Young Active Patient

EXAMINER

"A 42-year-old engineer presents with end-stage hip arthritis from prior acetabular fracture. He is very active (cycling, golf, occasional tennis). BMI 26. He asks about bearing surfaces and wants the best option for longevity. What do you recommend and why?"

EXCEPTIONAL ANSWER
This is an excellent question about bearing selection for a young, active patient who will require 40+ years of implant longevity. **Assessment:** This 42-year-old patient has a **40-50 year implant life requirement**. Wear and particle disease are the primary concerns over this timeframe. His activity level is moderate-to-high demand but not extreme impact. **Bearing Options:** I would discuss three main options: **Option 1 - Ceramic-on-Ceramic (my first choice):** This provides the **lowest wear rate** at 4-5 micrometers per year - approximately 10-20 times less than HXLPE. Modern fourth-generation ceramics like **Biolox Delta** (alumina matrix composite) have fracture risk under 0.1% and excellent 20-year data. The main concern is **squeaking (1-5% risk)**, which I would explain is usually benign but can be disturbing for some patients. Given his age and longevity requirement, this is my preferred option. **Option 2 - Ceramic-on-HXLPE:** This is an excellent **middle ground** - 30-50% less wear than metal-on-HXLPE, **no squeak risk**, and very forgiving. AOANJRR data shows this has the **lowest revision rates** in the under-55 age group. Many surgeons consider this the optimal bearing for young patients - best balance of wear performance and risk profile. **Option 3 - Metal-on-HXLPE (36mm head):** Still acceptable with modern HXLPE showing excellent longevity. However, wear rates are higher than ceramic options. I would choose this only if ceramic unavailable or cost prohibitive, ensuring adequate **liner thickness (minimum 6mm)** with the larger head. **My Recommendation:** I would recommend **ceramic-on-HXLPE as first choice**, with ceramic-on-ceramic as alternative if he accepts squeak risk for absolute lowest wear. I would reference **AOANJRR data** showing ceramic-on-HXLPE has lowest revision rates in his age group. **Counseling Points:** Whichever bearing we choose, I would emphasize proper component positioning is critical, activity modifications (avoid high-impact sports like rugby), and long-term follow-up to monitor for any complications.
KEY POINTS TO SCORE
42-year-old requires 40+ year implant longevity
Wear is the primary concern over this timeframe
Three main options: ceramic-on-ceramic, ceramic-on-HXLPE, metal-on-HXLPE
Ceramic-on-ceramic: lowest wear (4-5 micrometers/year) but 1-5% squeak risk
Ceramic-on-HXLPE: excellent balance - low wear, no squeak, AOANJRR shows lowest revision in under 55
Metal-on-HXLPE: acceptable if ceramic unavailable, ensure 6mm minimum liner thickness
Recommend ceramic-on-HXLPE as first choice for this patient
Counsel about activity modification (avoid extreme impact)
Reference AOANJRR data for evidence-based recommendation
Emphasize component positioning and long-term surveillance
COMMON TRAPS
✗Not discussing longevity requirements (40+ years needed)
✗Recommending small head (under 32mm) - increases dislocation risk
✗Not mentioning squeak risk with ceramic-on-ceramic
✗Forgetting to check liner thickness calculation with large heads
✗Not referencing AOANJRR registry data
LIKELY FOLLOW-UPS
"He asks specifically about metal-on-metal - his friend had this in 2006. What do you tell him?"
"How do you calculate minimum liner thickness? Walk me through the formula."
VIVA SCENARIOChallenging

Scenario 2: MoM Surveillance and Failure

EXAMINER

"A 58-year-old man had metal-on-metal THA (DePuy ASR) in 2007. He now presents with progressive hip pain over the past 6 months. Examination shows a palpable soft tissue mass laterally. X-rays show well-fixed components. Blood tests show cobalt 18 ppb, chromium 16 ppb. What is your management?"

EXCEPTIONAL ANSWER
This patient has a **metal-on-metal THA with concerning features** suggesting ALVAL (aseptic lymphocytic vasculitis-associated lesion) and pseudotumor formation. This is a **failed bearing technology** and requires urgent assessment and likely revision. **Immediate Assessment:** This presentation is highly concerning for **MoM failure**: - **Progressive pain** (not mechanical - suggests soft tissue reaction) - **Soft tissue mass** (pseudotumor) - **Elevated metal ions** (cobalt 18 ppb, chromium 16 ppb - well above 7 ppb threshold) - **DePuy ASR** (recalled system with high failure rates) - **Components well-fixed** (this is soft tissue problem, not loosening) **Next Investigation - MRI:** I would urgently arrange **MRI with MARS protocol** (metal artifact reduction sequence). This will show: - Size and location of pseudotumor - Extent of soft tissue destruction - Abductor muscle involvement - Fluid vs solid mass characteristics **MHRA 2012 Guidelines:** According to MHRA surveillance protocol, this patient meets **revision criteria**: - Symptomatic with pain - Soft tissue mass present - Metal ions over 7 ppb (his are over double this threshold) - ASR system (recalled device) **Surgical Management:** I would proceed with **revision THA**: **Surgical Steps:** 1. **Extended approach** for pseudotumor access (may need to extend standard posterior or lateral) 2. **Complete debridement** of all necrotic tissue, pseudotumor, and metallosis 3. **Assess bone loss** and abductor integrity 4. **Remove components** (both femoral and acetabular - change bearing surface) 5. **New bearing**: Ceramic-on-HXLPE or metal-on-HXLPE (**never metal-on-metal again**) 6. **Abductor repair** if detached or damaged 7. **Possible trochanteric slide** if extensive soft tissue destruction **Bearing Selection at Revision:** - **First choice**: Ceramic-on-HXLPE (eliminates metal at bearing, excellent wear) - **Alternative**: Metal-on-HXLPE (standard, proven) - **Never**: Metal-on-metal bearing again - **Consider dual mobility** if abductor damage creates instability risk **Patient Counseling:** I would explain this is a **failed technology** that was recalled. The metal debris has caused a severe soft tissue reaction. Surgery is required to prevent further tissue destruction. Outcomes depend on extent of damage, but with extensive pseudotumor and abductor involvement, he may have **residual weakness** and pain. This is **not his fault** - it is a known complication of this bearing type. **Post-operative:** - Abductor rehabilitation protocol if repaired - **No further metal ion monitoring** once MoM bearing removed - Standard THA follow-up with new bearing
KEY POINTS TO SCORE
MoM THA with progressive pain, mass, elevated ions - ALVAL/pseudotumor
DePuy ASR is recalled system with very high failure rates
Metal ions 18/16 ppb - well above 7 ppb threshold for concern
MRI MARS protocol urgently required to assess pseudotumor
MHRA 2012 guidelines: symptomatic + elevated ions = revision indicated
Surgical plan: debridement, component removal, bearing change, soft tissue repair
New bearing: ceramic-on-HXLPE or metal-on-HXLPE (never MoM again)
Consider dual mobility if abductor damage creates instability
Counsel about failed technology, realistic outcome expectations
Outcomes depend on extent of tissue destruction
COMMON TRAPS
✗Not recognizing this as ALVAL/MoM failure pattern
✗Delaying MRI (urgently required for surgical planning)
✗Not knowing MHRA 2012 surveillance guidelines
✗Attempting non-operative management (revision is indicated)
✗Not doing complete debridement (inadequate debridement leads to failure)
✗Not changing bearing surface (using metal bearing again)
✗Not counseling about potential poor outcomes with extensive tissue loss
LIKELY FOLLOW-UPS
"What is the MHRA 2012 surveillance protocol for asymptomatic MoM patients?"
"What is the pathophysiology of ALVAL? Why does this occur?"
VIVA SCENARIOCritical

Scenario 3: Squeaking Ceramic Hip

EXAMINER

"A 38-year-old woman had ceramic-on-ceramic THA 18 months ago. She now complains of loud squeaking with sitting to standing and climbing stairs. The hip is otherwise pain-free and functional. X-rays show well-positioned components. She is very distressed by the noise. How do you manage this?"

EXCEPTIONAL ANSWER
This is a challenging scenario of **ceramic-on-ceramic squeaking** - a known complication occurring in 1-5% of cases. The key question is whether this represents a **benign phenomenon** or indicates a mechanical problem requiring intervention. **Assessment:** The clinical picture suggests **benign squeaking**: - **Specific activities** trigger noise (sit-to-stand, stairs - typical pattern) - **Pain-free** (critical - most squeaking is not painful) - **Good function** - **Well-positioned components** on X-ray - **18 months post-op** (typical onset is 6-24 months) However, patient is **significantly distressed** - this affects quality of life even if mechanically benign. **Further Assessment:** I would perform detailed investigation: **1. Component Position Analysis:** - Measure **cup inclination** (target 40 degrees plus/minus 10) - Measure **cup anteversion** (target 15-20 degrees) - Assess **combined anteversion** (femoral + acetabular) - Look for **impingement** (neck-liner, neck-cup) - **Edge loading** from malposition causes stripe wear **2. Patient Factors:** - **BMI** (thin patients higher risk - less soft tissue dampening) - **Activity pattern** (high activity increases microseparation) - **Psychological impact** (how much is this affecting life quality?) **3. Advanced Imaging:** - **CT scan** to accurately measure 3D component position - Look for **stripe wear** (linear wear pattern from edge loading) - Assess for **early osteolysis** (rare at 18 months but possible) **Understanding Squeaking Mechanism:** Squeaking occurs from **microseparation** and rapid re-engagement of ceramic surfaces: - **Edge loading** from malposition or impingement - **Thin patients** (less damping) - **High moment arm activities** (sit-to-stand, stairs) - Usually **benign** but occasionally indicates mechanical problem **Management Options:** **Non-Operative (my first approach):** 1. **Reassurance and education**: - Explain squeaking is **common (1-5%)** and usually **benign** - **Not associated with higher revision rates** in most studies - **Not causing damage** in majority of cases - May **improve over time** (some resolve spontaneously) 2. **Activity modification**: - Certain activities may be modified to reduce squeak - Avoid extreme hip flexion moments - **Weight reduction** if appropriate (reduces joint loads) 3. **Surveillance**: - **6-month review** with X-rays - Monitor for **stripe wear progression** (concerning if worsening) - Monitor for **pain development** (changes management) - Annual follow-up long-term **Operative Indications:** I would consider **revision** only if: - **Progressive stripe wear** (risk of ceramic fracture) - **Development of pain** (suggests mechanical problem) - **Component malposition** requiring correction - **Patient distress severe** AND patient accepts revision risks after trial of non-operative management **If Revision Needed:** - **Bearing change** to ceramic-on-HXLPE or metal-on-HXLPE - **Correct malposition** (revise cup if malaligned) - Never use ceramic-on-ceramic again (will likely squeak again) **Counseling This Patient:** I would have an honest discussion: - Squeaking is **frustrating but usually benign** - X-rays show **good position and no wear** - **Observation** is safest approach initially - **Revision is major surgery** with risks (infection, dislocation, fracture) - Revision **doesn't guarantee** noise resolution - **Trial of 6-12 months** observation before considering revision - Some squeaking **resolves spontaneously** I would **not rush to revision** for isolated squeaking without pain or mechanical problems. The risks of revision outweigh benefits in most cases. However, if quality of life is severely affected and conservative management fails, revision to alternative bearing is reasonable after thorough counseling.
KEY POINTS TO SCORE
Ceramic squeaking occurs in 1-5% - known complication of CoC
Most squeaking is benign and not associated with higher revision rates
This patient: pain-free, well-positioned, functional - suggests benign squeak
Assess component position carefully (malposition increases squeak risk)
Consider CT to measure 3D position and look for stripe wear
First-line: reassurance, education, activity modification
Monitor for progression, pain development, or stripe wear
Revision only if: progressive wear, pain develops, severe patient distress after conservative trial
If revision: change bearing to ceramic-on-HXLPE or MoP (not CoC again)
Never rush to revision for isolated benign squeaking
COMMON TRAPS
✗Immediately recommending revision without trial of conservative management
✗Not measuring component position accurately
✗Not explaining that squeaking is usually benign
✗Not counseling about revision risks vs benefits
✗Missing stripe wear on imaging (concerning finding)
✗Not considering patient's quality of life impact vs surgical risks
✗Promising revision will definitely solve the squeaking
LIKELY FOLLOW-UPS
"What is stripe wear and why is it concerning?"
"If you revise this patient, what bearing would you use and why?"
"What is the mechanism of ceramic squeaking?"

MCQ Practice Points

HXLPE Mechanism

Q: How does highly cross-linked polyethylene reduce wear compared to conventional polyethylene? A: Irradiation (gamma or e-beam) creates cross-links between polymer chains, increasing wear resistance. Post-irradiation treatment (remelting or annealing) eliminates free radicals. This results in 90% wear reduction but decreased mechanical properties (fatigue strength). Minimum 6mm thickness required.

Ceramic Fracture Risk

Q: What is the fracture risk of modern fourth-generation ceramic bearings (Biolox Delta)? A: Under 0.1% (less than 1 in 1000). Biolox Delta is alumina matrix composite with zirconia platelets for increased fracture toughness. This is much lower than first-generation pure alumina (1%) and second-generation (0.2-0.5%). Still, fracture is catastrophic requiring extensive debridement.

MoM Failure

Q: What is ALVAL and how does it lead to metal-on-metal THA failure? A: ALVAL (Aseptic Lymphocytic Vasculitis-Associated Lesion) is a Type IV delayed hypersensitivity reaction to chromium and cobalt ions released from MoM bearings. Results in lymphocytic infiltration, tissue necrosis, and pseudotumor formation with progressive soft tissue destruction. Diagnosed by elevated metal ions (over 7 ppb) and MRI showing pseudotumor.

Dual Mobility Mechanism

Q: How does dual mobility reduce dislocation risk compared to standard bearings? A: Dual mobility has two articulations: small inner head (22-28mm) in polyethylene liner, and large outer liner (36-42mm+) in metal shell. This creates large effective head size for stability while maintaining small inner bearing. Results in 50-75% dislocation reduction in high-risk patients. Main complication is intraprosthetic dislocation (IPD) under 1%.

AOANJRR Bearing Data

Q: According to AOANJRR, which bearing has the lowest revision rate in patients under 55? A: Ceramic-on-HXLPE shows the lowest revision rates in the under-55 age group at 15-year follow-up (approximately 4-5%), followed by ceramic-on-ceramic and metal-on-HXLPE (5-7%). Metal-on-metal has highest revision rates (15-30%) and is obsolete. In patients over 65, metal-on-HXLPE is excellent and cost-effective.

Particle Disease

Q: What particle size range is most osteolytic in polyethylene wear debris? A: 0.1-10 micrometers is the most biologically active size range. These particles are phagocytosed by macrophages, triggering cytokine release (TNF-alpha, IL-1, RANKL) and osteoclast activation. HXLPE dramatically reduces particle generation, resulting in 95% reduction in osteolysis vs conventional PE at 10-year follow-up.

Head Size Selection

Q: What is the optimal femoral head size for metal-on-HXLPE bearing in standard patient? A: 32-36mm represents optimal balance. Larger heads reduce dislocation risk and increase ROM, but increase volumetric wear. Heads under 28mm have unacceptably high dislocation rates. Heads over 40mm provide no additional stability benefit and may increase wear. Must ensure minimum 6mm liner thickness with larger heads.

Australian Context

AOANJRR - world's most comprehensive joint registry:

The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) tracks over 95% of joint replacements performed in Australia since 1999. This provides Level 1 evidence for bearing performance.

Key AOANJRR findings on bearing surfaces (2023 Annual Report):

Primary THA revision rates at 15 years:

  1. Ceramic-on-HXLPE: Lowest revision rate (approximately 4-5%)
  2. Metal-on-HXLPE: Second lowest (approximately 5-6%)
  3. Ceramic-on-Ceramic: Similar to MoP (5-7%)
  4. Metal-on-Metal: Highest revision rate (15-30% at 15 years) - obsolete

Age-specific findings:

  • Under 55 years: Ceramic-on-HXLPE and Ceramic-on-Ceramic show lower revision rates than MoP
  • 55-65 years: Ceramic-on-HXLPE advantage narrows
  • Over 65 years: MoP (HXLPE) excellent outcomes, cost-effective choice

Dual mobility outcomes:

  • Revision THA: Significantly lower dislocation rate vs conventional bearings
  • Primary THA in high-risk patients: Lower revision for dislocation
  • No increase in aseptic loosening or other complications
  • Rapidly increasing usage (now 5-10% of primary THAs)

Head size findings:

  • Optimal: 32-36mm for most bearings
  • Under 28mm: Higher dislocation rate (avoid)
  • Over 40mm: No additional benefit, potential increased wear in MoP

Registry Data in Exam Answers

Always reference AOANJRR data when discussing bearing selection in Australian exam context. Example: "According to AOANJRR 2023 report, ceramic-on-HXLPE shows lowest revision rates in patients under 55, while metal-on-HXLPE is excellent and cost-effective in patients over 65." This demonstrates evidence-based practice.

Bearing trends in Australia (AOANJRR data):

  • HXLPE dominance: Over 90% of primary THAs use HXLPE liner (MoP or CoP)
  • Ceramic growth: Ceramic heads increasing (now 15-20% of primaries)
  • Dual mobility expansion: Growing from under 1% (2010) to 5-10% (2023)
  • MoM abandonment: Essentially zero new implants (under 0.1%)

Current Australian practice patterns (2024):

Bearing distribution in primary THA:

  • Metal-on-HXLPE: 70-80% (most common, standard of care)
  • Ceramic-on-HXLPE: 10-15% (growing, especially young patients)
  • Ceramic-on-Ceramic: 5-10% (selected young, active patients)
  • Dual Mobility: 5-10% (high-risk instability patients)
  • Metal-on-Metal: Under 0.1% (essentially abandoned)

AOANJRR recommendations:

  • HXLPE is standard - conventional PE obsolete
  • 32-36mm heads optimal for most patients
  • Ceramic options for young patients (under 55) show lower revision rates
  • Dual mobility excellent for instability risk in primary and revision
  • MoM surveillance continues for legacy patients

Regulatory framework:

  • TGA approval required for all bearing surfaces
  • MoM surveillance mandated for legacy patients (MHRA 2012 equivalent)
  • Registry participation over 95% of Australian THAs
  • Informed consent must include bearing-specific risks

Australian epidemiology: THA is one of the most common elective procedures in Australia, with over 30,000 primary procedures performed annually. The average patient age is 65-70 years, with younger patients (under 55) comprising approximately 15% of cases. Age-standardized rates are increasing due to population aging and expanded indications.

Management considerations in Australian practice:

THA BEARING SURFACES

High-Yield Exam Summary

BEARING OPTIONS OVERVIEW

  • •Metal-on-HXLPE: 70-80% of THAs, standard of care, excellent outcomes
  • •Ceramic-on-HXLPE: 10-15%, best for young patients, no squeak
  • •Ceramic-on-Ceramic: 5-10%, lowest wear, 1-5% squeak risk
  • •Dual Mobility: 5-10% primary (higher in revision), 50-75% dislocation reduction
  • •Metal-on-Metal: Obsolete (under 0.1%), ALVAL/pseudotumor failure

HXLPE (HIGHLY CROSS-LINKED PE)

  • •Manufacturing: Irradiation (50-100 kGy) + remelting/annealing
  • •Benefits: 90% wear reduction vs conventional PE, 95% less osteolysis
  • •Trade-off: Decreased mechanical properties (fatigue strength)
  • •Minimum thickness: 6mm to prevent fracture
  • •Used in over 90% of modern THAs globally

CERAMIC BEARINGS

  • •CoC: Lowest wear (4-5 micrometers/year), 1-5% squeak, under 0.1% fracture (Biolox Delta)
  • •CoP (ceramic-on-HXLPE): 30-50% less wear than MoP, no squeak, excellent for young
  • •Indications: Young patients (under 50), high longevity requirements
  • •Avoid: High-impact sports (rugby, martial arts), extreme trauma risk
  • •AOANJRR: CoP lowest revision rate in under 55 age group

MOM FAILURE (LEGACY SURVEILLANCE)

  • •ALVAL: Type IV hypersensitivity to Co/Cr ions → pseudotumor
  • •Surveillance (MHRA 2012): Annual metal ions, MRI if symptomatic or ions over 7 ppb
  • •Revision if: Symptomatic + pseudotumor, or ions over 20 ppb
  • •At revision: Complete debridement, bearing change (never MoM again)
  • •Essentially abandoned globally - under 0.1% current usage

DUAL MOBILITY

  • •Design: Small inner head (22-28mm) in PE liner, large outer (36-42mm+) effective
  • •Dislocation reduction: 50-75% in high-risk patients
  • •Indications: Revision THA, abductor deficiency, neurologic/cognitive impairment
  • •Complication: Intraprosthetic dislocation (IPD) under 1%, requires open reduction
  • •AOANJRR: 1-2% dislocation rate vs 3-5% conventional in revision THA

SELECTION BY PATIENT

  • •Standard (over 65): MoP (HXLPE) 32-36mm head - proven, cost-effective
  • •Young active (under 50): CoP or CoC - longevity priority, counsel squeak risk
  • •Instability risk: Dual mobility first choice - dramatic dislocation reduction
  • •Metal allergy: CoC or CoP - avoid metal bearing surfaces
  • •Obesity: MoP or CoP, ensure adequate liner thickness (over 6mm)

AOANJRR KEY DATA

  • •Ceramic-on-HXLPE: Lowest revision rate (4-5% at 15 years), especially under 55
  • •Metal-on-HXLPE: Excellent all ages (5-6% at 15 years), cost-effective
  • •Head size: 32-36mm optimal balance (dislocation vs wear)
  • •Dual mobility: Significantly lower dislocation in revision THA
  • •Always reference registry data in Australian exam answers

COMPLICATIONS

  • •HXLPE: Liner fracture if under 6mm thickness
  • •CoC: Squeaking 1-5% (usually benign), fracture under 0.1% (catastrophic)
  • •CoC: Stripe wear from malposition (can progress to fracture)
  • •MoM: ALVAL/pseudotumor 10-30% at 10 years, surveillance mandatory
  • •Dual mobility: IPD under 1%, requires open reduction

EXAM PEARLS

  • •HXLPE solved the particle disease problem - 90% wear reduction
  • •Ceramic-on-HXLPE best balance for young patients (low wear, no squeak)
  • •MoM failed due to ALVAL - know MHRA 2012 surveillance protocol
  • •Dual mobility transforms instability outcomes - 50-75% dislocation reduction
  • •Reference AOANJRR data for evidence-based Australian practice
Quick Stats
Reading Time180 min
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