S2-Alar-Iliac & Iliac Screws
- Long fusions ending at the sacrum put large cantilever loads on the S1 screws and the lumbosacral junction; sacropelvic fixation extends the construct into the pelvis to protect S1, share the load and improve fusion
- Indications: long deformity constructs reaching the sacrum, sacral or pelvic instability, high-grade spondylolisthesis
- The iliac screw is strong but usually needs an offset connector and its head can be prominent
- The S2AI screw crosses the SI joint from the S2 ala into the ilium, in-line with the pedicle screws, more medial and deeper, and is now widely favoured
- The S2AI path lies close to major neural and vascular structures, so placement must be accurate
- The characteristic S2AI complication is SI joint pain; screw fracture, set-screw dislodgement and periscrew lucency also occur
- Pelvic fixation usually fails around the screw, not at it: rod fracture or pseudarthrosis across the lumbosacral junction; more rods across the junction, an accessory rod to S2 or the ilium, and coronal correction protect it
- “Sacropelvic fixation extends long fusions to the PELVIS to PROTECT S1 screws and the lumbosacral junction (high pseudarthrosis zone).
- “Iliac screw = strong but needs OFFSET CONNECTORS and can be prominent; S2AI screw = in-line with pedicle screws, more medial/deeper, crosses the SI joint - generally favoured.
- “S2AI path is near neurovascular structures (robotic guidance over 95% accuracy reported - from a technical review, not a comparative trial); complications = SI joint pain 3.2%, screw fracture 1.9%, set-screw dislodgement 2.2%, revision 1.6% (312 screws).
- “Prominence, quantified: S2AI 1.9% (12/648) vs iliac 6.3% (51/814); removed for prominence 0/12 vs 14/51. That is the evidence behind 'S2AI is less prominent'.
- “Failure is usually NOT the anchor: 7 of 11 pelvic fixation failures were rod fracture or pseudarthrosis at the lumbosacral junction. More rods across the junction (OR 0.15) and accessory rod to S2/ilium not S1 (OR 0.2) protect it; residual coronal malalignment (OR 1.5) is the modifiable risk.
Rationale & the Two Screws
Why the pelvis. When a long fusion ends at the sacrum, the S1 pedicle screws and the lumbosacral junction bear enormous cantilever loads, and this high-stress zone has a high rate of S1-screw loosening and pseudarthrosis. Sacropelvic fixation extends the construct into the pelvis to protect the S1 screws, share the load and improve the chance of fusion across the junction. It is indicated for long deformity constructs reaching the sacrum, for sacral or pelvic instability and for high-grade spondylolisthesis.
The iliac screw. The traditional anchor is placed into the ilium between the inner and outer tables, aiming towards the anterior inferior iliac spine, and gives strong fixation. Because the screw sits laterally and off-axis to the main rod, it usually needs an offset connector to join the construct, and its head can be prominent and symptomatic.
The S2-alar-iliac screw. The S2AI screw starts on the S2 ala, crosses the sacroiliac joint and enters the ilium. It was introduced specifically to decrease strain on the S1 screws and improve fixation across the lumbosacral junction, and crossing the cortical surfaces of the SI joint makes it biomechanically strong.
Its trajectory lies roughly in line with the proximal pedicle screws, which avoids offset connectors, and it sits more medial and deeper, so it is less prominent. It is effective with generally low complication rates and is now widely favoured, although the iliac screw remains a strong alternative.
Prominence, measured. A meta-analysis of 18 studies and 1,462 patients turned "S2AI is less prominent" from an assertion into a measured difference. Symptomatic screw prominence occurred in 1.9% (12 of 648) with S2AI against 6.3% (51 of 814) with iliac screws. None of the 12 symptomatic S2AI screws was removed, against 14 of the 51 iliac screws (27.5%), so iliac prominence is both commoner and more often needs a second operation.

The Lumbosacral Junction: Pivot Point and Anterior Column Support
The pivot point. McCord and colleagues defined a lumbosacral pivot point around the middle column at the L5-S1 disc. The bending moment a distal anchor must resist depends on how far anterior to this point it reaches.
Why S1 screws loosen. S1 screws end at or behind the pivot point, so they see a huge cantilever load and loosen. Iliac and S2AI screws extend the construct anterior to the pivot point, giving a long lever arm and far greater resistance to flexion, which is the biomechanical reason pelvic fixation protects S1.
Anterior column support. An interbody cage or ALIF at L5-S1 also improves load-sharing: it offloads the posterior screws, reduces S1 strain and lowers lumbosacral pseudarthrosis. Pelvic fixation and anterior column support are complementary solutions to the same high-stress junction.
Placement Landmarks and What to Avoid
S2AI entry and trajectory. The entry is just inferior and lateral to the S1 dorsal foramen, on the S2 ala. Aim caudally, laterally and anteriorly to cross the SI joint into the ilium between the inner and outer tables, directed above the sciatic notch towards the AIIS.
Iliac screw entry and trajectory. The entry is at or just below the PSIS, aiming towards the AIIS between the tables. The entry is often recessed, or an offset connector used.
Confirming the corridor. On an obturator-outlet fluoroscopic view the bony corridor is seen as the "teardrop", which confirms a safe path between the tables. Confirm containment with intra-operative imaging or navigation; detailed robotic and navigation technique is covered in Navigation & Robotics in Spine Surgery.
Accuracy. The S2AI path is intimately associated with major neural and vascular structures and the SI joint, so accurate placement matters. Robotic guidance obtains the correct trajectory with over 95% accuracy, a figure from a technical review rather than a comparative trial.
What to avoid. Accurate placement depends on knowing exactly what a malpositioned screw endangers:
- The sciatic notch, with the sciatic nerve and superior gluteal vessels - stay above it
- The hip joint and acetabulum, if the screw runs too caudal or anterior
- The anterior iliac cortex, near the iliac vessels
Technique Considerations & Complications
The joint it crosses. The feature that makes the S2AI screw strong, crossing the sacroiliac joint, is also the source of its commonest specific complication, SI joint pain or irritation. In a consecutive series of 312 S2AI screws the recognised complications were:
- SI joint pain 3.2%, most improving after an SI joint block
- Periscrew lucency 2.2%
- Set-screw dislodgement 2.2%
- Screw fracture 1.9%, mostly at the neck
- Revision for screw failure 1.6%
Distal construct failure can also occur around the lumbopelvic region. Patients should be counselled about SI-joint symptoms, screw fracture and set-screw problems.
How Pelvic Fixation Actually Fails - and What Protects It
Failure in proportion. Pelvic fixation failure is usually discussed as "screw problems", but in practice the construct more often fails around the screws than at them. In 253 adult-deformity patients instrumented over at least six levels and followed for two years, pelvic fixation failed in 11 (4.3%), by these mechanisms:
- n
- 4
- What it tells you
- The commonest single mechanism - the rod, not the screw, is the weak link
- n
- 3
- What it tells you
- The biological failure the whole construct exists to prevent
- n
- 1
- What it tells you
- Implant failure at the anchor itself is comparatively uncommon
- n
- 1
- What it tells you
- As above - fixation loss is not the dominant mode
- n
- 1
- What it tells you
- Bone fails around a well-fixed anchor, particularly in poor bone stock
- n
- 1
- What it tells you
- The prominence problem that drives the S2AI-versus-iliac choice
The junction becomes the weak point. Seven of the eleven failures were rod fracture or pseudarthrosis at the lumbosacral junction, not a failure of the pelvic anchor. Adding a pelvic screw protects S1, but the junction it protects then becomes the highest-strain point in the construct, and it is the rod crossing that junction that breaks.
What protects it. In the same cohort two construct choices were protective and one alignment variable was a risk factor:
- More rods crossing the lumbopelvic junction. Non-failures had a mean of 3.8 rods crossing it against 2.9 in failures (p = 0.009), and on multivariate analysis the number crossing was protective, OR 0.15 (p = 0.002)
- An accessory rod taken down to S2 or the ilium rather than stopping at S1 (OR 0.2, p = 0.004), present in 54.2% of the non-failures against 18.2% of the failures. Stopping the accessory rod at S1 leaves the very junction that fails without any buttress
- Residual coronal malalignment, measured as a worse post-operative C7 coronal vertical axis, was an independent risk factor (OR 1.5, p = 0.028)
The modifiable variable. Coronal malalignment is the one genuinely modifiable intra-operative variable in that list. Correcting coronal balance protects the lumbopelvic construct, while leaving the patient coronally off-centre loads it eccentrically until something breaks, so correct the coronal plane, not only the sagittal.
The cohort. Mean pelvic screw diameter and length were 8.6 mm and 87 mm, an L5-S1 interbody was used in 74.7%, all rods crossing the lumbosacral junction were cobalt-chrome, and all pelvic screws were closed-headed tulips.
The multirod vocabulary. "Add another rod" is imprecise, and the supplementary rods have distinct definitions worth using correctly. The accessory rod is the one relevant at the lumbosacral junction.
- Definition
- The longest rod, running from the bottom of the construct to the upper instrumented vertebra
- Where it is used
- Every construct
- Definition
- Shorter than the primary and connected directly to pedicle screws (fewer of them), joined to the primary by lateral connectors or cross-links
- Where it is used
- Adds overall stiffness
- Definition
- A four-rod technique in which two rods span only the osteotomy site via the screws above and below, NOT connected to the primary rod
- Where it is used
- Three-column osteotomy sites
- Definition
- Connected to the primary rod by side connectors, buttressing it where rod strain is highest
- Where it is used
- Three-column osteotomies AND the lumbosacral junction - the relevant one here
- Definition
- Spans an osteotomy and is deliberately NOT contoured to the restored lordosis, buttressing the primary rod above and below
- Where it is used
- Pedicle subtraction osteotomy
- Definition
- Secured to a separate iliac screw on the side of truncal shift and connected to the primary rod; distracted against to correct a coronal curve
- Where it is used
- Coronal malalignment correction
Mnemonics & Memory Aids
PELVIS
Hook:PELVIS: Protect S1, Extend to pelvis, Lumbopelvic load shared, Vessels/nerves near, Iliac vs S2AI, SI joint crossed (watch pain).
Clinical Decision Scenarios
Practise clinical reasoning and management decisions out loud
“Why and when would you extend a long spinal construct to the pelvis, and how?”
“What complications are specific to S2-alar-iliac fixation?”
“You have taken a fourteen-level fusion down to the pelvis with bilateral S2AI screws. Eighteen months later the patient has new back pain and a broken rod at L5-S1. What went wrong, and what would you have done differently?”
Why & when
- Long fusions to the sacrum overload S1 / the lumbosacral junction (pseudarthrosis zone)
- Pelvic fixation protects S1, shares load, improves fusion
- Also: sacropelvic instability, high-grade spondylolisthesis
Iliac screw
- Into the ilium (between tables, towards AIIS) - strong purchase
- Usually needs an offset connector to reach the rod
- Screw head can be prominent/symptomatic
S2-alar-iliac (S2AI)
- From S2 ala across the SI joint into the ilium
- In-line with pedicle screws (no offset connector), more medial/deeper (less prominent)
- Strong (crosses SI joint cortices); path near neurovascular structures (robotic guidance over 95%)
Complications (312 S2AI screws)
- SI joint pain/irritation 3.2% (most settle after an SI joint block)
- Periscrew lucency 2.2%; set-screw dislodgement 2.2%
- Screw fracture 1.9% (usually at the neck); revision for screw failure 1.6%
- Prominence: S2AI 1.9% vs iliac 6.3%; removed 0/12 vs 14/51
Failure & how to prevent it
- 2-yr pelvic fixation failure 4.3% (11/253) in long ASD constructs
- 7 of 11 = ROD FRACTURE or PSEUDARTHROSIS at the lumbosacral junction, not the anchor
- Protective: more rods across the lumbopelvic junction (OR 0.15)
- Protective: accessory rod down to S2/ilium rather than S1 (OR 0.2)
- Risk: residual coronal malalignment, worse C7 CVA (OR 1.5) - modifiable
- Typical pelvic screw 8.6 mm x 87 mm; cobalt-chrome rods; L5-S1 interbody in ~75%
Evidence & Key Studies
Durability and failure types of S2-alar-iliac screws: 312 consecutive screws
- S2AI screws improve stability across the lumbosacral junction by crossing the cortical surfaces of the sacroiliac joint, and clinical outcomes (back pain, ambulation, ODI) improved significantly.
- SI joint pain occurred in 3.2% (most improved after an SI joint block); periscrew lucency in 2.2%, set-screw dislodgement in 2.2%, and screw fracture in 1.9% (mostly neck fractures).
- Revision for S2AI screw failure was needed in 1.6%; SI-joint irritation occurred with considerable frequency.
S2AI versus iliac screw prominence and removal: systematic review and meta-analysis
- Eighteen studies and 1,462 patients (648 S2AI, 814 iliac) were pooled to compare symptomatic screw prominence and removal between the two techniques.
- Symptomatic prominence was significantly lower with S2AI: 1.9% (12/648) versus 6.3% (51/814) for iliac screws, pooled RR difference 0.08 (p < 0.001), with low heterogeneity (I-squared 3.32%).
- Of the symptomatic screws, none of the S2AI screws (0/12) were removed for prominence against 27.5% (14/51) of iliac screws - so iliac prominence is not only commoner but more often needs an operation.
Incidence, mechanism and protective strategies for 2-year pelvic fixation failure after adult spinal deformity surgery
- Among 253 adult deformity patients with at least six instrumented levels and pelvic fixation, the 2-year pelvic fixation failure rate was 4.3% (11 patients); mean pelvic screw diameter and length were 8.6 mm and 87 mm.
- Seven of the 11 failures were rod fracture (4) or pseudarthrosis (3) across the lumbosacral junction rather than failure of the pelvic anchor itself.
- More rods crossing the lumbopelvic junction (OR 0.15, p = 0.002) and an accessory rod reaching S2 or the ilium rather than S1 (OR 0.2, p = 0.004) were protective, while worse post-operative coronal vertical axis was an independent risk factor (OR 1.5, p = 0.028).
The lexicon of multirod constructs in adult spinal deformity: when, why and how
- Defines the supplementary rods whose names are used inconsistently in practice: primary, secondary, satellite, accessory, delta and kickstand.
- Accessory rods connect to the primary rod by side connectors and buttress it where rod strain is highest - explicitly including the lumbosacral junction as well as three-column osteotomy sites.
- Multirod use grew alongside deformity correction specifically to prevent rod fracture and pseudarthrosis at high-strain points.
Robotic versus freehand S2-alar-iliac fixation: technical considerations
- The S2AI trajectory was introduced to decrease strain on the S1 screws and, by aligning with the proximal pedicle screw instrumentation, avoids the offset connectors needed for traditional iliac screws.
- S2AI screws are effective with low complication rates, but their path is intimately associated with major neural and vascular structures.
- Robotic guidance obtains the correct S2AI trajectory safely and effectively with over 95% accuracy.
The biomechanical rationale (S2AI screws crossing the SI-joint cortices to improve lumbosacral stability), the improved clinical outcomes and the specific complications (SI joint pain 3.2%, periscrew lucency 2.2%, set-screw dislodgement 2.2%, screw fracture 1.9%, revision 1.6%, all from 312 consecutive screws) come from the cited Hyun series. The quantified prominence advantage of S2AI over the iliac screw - 1.9% of 648 versus 6.3% of 814, and 0 of 12 versus 14 of 51 removed - is the cited Garcia meta-analysis of 18 studies, and is what turns "S2AI is less prominent" from an assertion into a measured difference. The failure mechanisms, the protective effect of more rods across the lumbopelvic junction and of an accessory rod reaching S2 or the ilium, the coronal-alignment risk factor, and the 8.6 mm by 87 mm mean screw dimensions come from the cited Lee series; the definitions of the supplementary rods from the cited Ramey lexicon.
The S2AI trajectory's purpose (decreasing S1 strain), its in-line alignment avoiding offset connectors, its proximity to neurovascular structures, and the over-95% accuracy figure for robotic guidance come from the cited Laratta paper - which is a technical review rather than a comparative trial, so the figure describes what robotic placement achieves and is not evidence that it outperforms accurate freehand or navigated placement. The indications for pelvic fixation, the iliac-screw technique and the placement landmarks are standard, well-established teaching. (See also Adult Spinal Deformity and Spondylolisthesis for high-grade slips.)